Pimkov, Igor V. published the artcileDesigning the Molybdopterin Core through Regioselective Coupling of Building Blocks, Recommanded Product: 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, the publication is Chemistry – A European Journal (2015), 21(47), 17057-17072, database is CAplus and MEDLINE.
2-Amino-5,6,7,8-tetrahydro-6-[3-hydroxy-1,2-dimercapto-4-(phosphonooxy)-1-buten-1-yl]-4(3H)-pteridinone (i.e. molybdopterin) is an essential cofactor for all forms of life. The cofactor is composed of a pterin moiety appended to a dithiolene-functionalized pyran ring, and through the dithiolene moiety it binds metal ions. Different synthetic strategies for dithiolene-functionalized pyran precursors that have been designed and synthesized are discussed. These precursors also harbor 1,2-diketone or osone (i.e., monosaccharide, osulose) functionality that has been condensed with 1,2-diaminobenzene or other heterocycles resulting in several quinoxaline or pterin derivatives Use of additives improves the regioselectivity of the complexes. The mols. have been characterized by 1H and 13C NMR and IR spectroscopies, as well as by mass spectrometry. In addition, several compounds have been crystallog. characterized. The geometries of the synthesized mols. are more planar than the geometry of the cofactor found in proteins. The synthesis of the target compounds was achieved using 4,4-dimethyl-2-thioxo-4H-1,3-dithiolo[4,5-c]pyran-6,7-dione, 4,4-dimethyl-4H-1,3-dithiolo[4,5-c]pyran-2,6,7-trione as key intermediates. The title compounds thus formed included 4,4-dimethyl-4H-1,3-dithiolo[4,5]pyrano[2,3-b]quinoxaline-2-thione,.
Chemistry – A European Journal published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, Recommanded Product: 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran.
Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics