Gounden, Verena published the artcileA pilot study: Bisphenol-A and Bisphenol-A glucuronide levels in mother and child pairs in a South African population, Synthetic Route of 267244-08-6, the publication is Reproductive Toxicology (2019), 93-99, database is CAplus and MEDLINE.
Exposure to Bisphenol A (BPA) during early development particularly in- utero has been linked to a wide range of pathol. The aim of this study was to determine serum levels of BPA and its naturally occurring metabolite BPA-glucuronide (BPA-g) in South African mother-child pairs. Third-trimester serum maternal samples and matching cord blood samples were analyzed for BPA and BPA-g using LC-MS/MS. Ninety maternal and child pairs were analyzed. BPA was detectable in more than 25% of maternal and cord blood samples. Spearman correlation demonstrated significant pos. correlation between maternal and child BPA and BPA-g levels with correlation coefficients of 0.892 and 0.744, resp. A significant pos. association between cord BPA levels and child birth-weight (p = 0.02) as well as with maternal BMI (p = 0.04) was noted. This is the first study to describe the presence of detectable BPA levels using LC-MS/MS methodol. in a South African population.
Reproductive Toxicology published new progress about 267244-08-6. 267244-08-6 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Chiral,Carboxylic acid,Benzene,Phenol,Alcohol,Ether,, name is (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(4-(2-(4-hydroxyphenyl)propan-2-yl)phenoxy)tetrahydro-2H-pyran-2-carboxylic acid, and the molecular formula is C21H24O8, Synthetic Route of 267244-08-6.
Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics