Hu, Li-Xin’s team published research in Chemosphere in 284 | CAS: 69097-99-0

Chemosphere published new progress about 69097-99-0. 69097-99-0 belongs to tetrahydropyran, auxiliary class Other Aliphatic Heterocyclic,Benzene,Phenol,Ether,Inhibitor, name is 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, and the molecular formula is C16H14O6, SDS of cas: 69097-99-0.

Hu, Li-Xin published the artcileWhat is in Nigerian waters? Target and non-target screening analysis for organic chemicals, SDS of cas: 69097-99-0, the publication is Chemosphere (2021), 131546, database is CAplus and MEDLINE.

Emerging organic contaminants (e.g., active pharmaceutical ingredients and personal care products ingredients) are ubiquitous in the environment and potentially harmful to ecosystems, have gained increasing public attention worldwide. Nevertheless, there is a scarcity of data on these contaminants in Africa. In this study, various types of water samples (wastewater, surface water and tap water) collected from Lagos, Nigeria were analyzed for these chems. by both target and non-target anal. on an UHPLC-Orbitrap-MS/MS. In total, 109 compounds were identified by non-target screening using the online database mzCloud. Level 1 identification confidence was achieved for 13 compounds for which reference standards were available and level 2 was achieved for the rest. In the quant. anal., 18 of 38 target compounds were detected, including the parent compounds and their metabolites. Acetaminophen, sulfamethoxazole, acesulfame, and caffeine were detected in all samples with their highest concentrations at 8000, 5300, 16, and 7700μg/L in wastewater, 140000, 3300, 7.7, and 12000μg/L in surface water, and 66, 62, 0.17 and 1000μg/L in tap water, resp. The occurrence of psychoactive substances, anticancer treatments, antiretrovirals, antihypertensives, antidiabetics and their metabolites were reported in Nigeria for the first time. These results indicate poor wastewater treatment and management in Nigeria, and provide a preliminary profile of organic contaminants occurring in Nigerian waters. The findings from this study urge more future research on chem. pollution in the aquatic environments in Nigeria.

Chemosphere published new progress about 69097-99-0. 69097-99-0 belongs to tetrahydropyran, auxiliary class Other Aliphatic Heterocyclic,Benzene,Phenol,Ether,Inhibitor, name is 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, and the molecular formula is C16H14O6, SDS of cas: 69097-99-0.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Hikino, Hiroshi’s team published research in Chemical & Pharmaceutical Bulletin in 23 | CAS: 27943-46-0

Chemical & Pharmaceutical Bulletin published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, Product Details of C10H16O2.

Hikino, Hiroshi published the artcileSteroids. XXIV. Shidasterone, an insect metamorphosing substance from Blechnum niponicum. Structure, Product Details of C10H16O2, the publication is Chemical & Pharmaceutical Bulletin (1975), 23(7), 1458-79, database is CAplus and MEDLINE.

The structure of shidasterone (I), the phytoecdysone isolated from B. niponicum (Blechnaeceae) was determined Stereoisomers of the cholestane-20,22-diol derivatives were synthesized and their chem. and spectral properties were examined.

Chemical & Pharmaceutical Bulletin published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, Product Details of C10H16O2.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Torii, Sigeru’s team published research in Tetrahedron in 49 | CAS: 27943-46-0

Tetrahedron published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C12H20O6, Synthetic Route of 27943-46-0.

Torii, Sigeru published the artcileSyntheses of chromones and quinolones via palladium-catalyzed carbonylation of o-iodophenols and anilines in the presence of acetylenes, Synthetic Route of 27943-46-0, the publication is Tetrahedron (1993), 49(31), 6773-84, database is CAplus.

Synthesis of 2-substituted chromones and quinolones has been performed by a Pd-catalyzed carbonylation of o-iodophenols or o-iodoanilines in the presence of terminal acetylenes in a high yield through coupling of halides and acetylenes followed by cyclization as a one-pot reaction.

Tetrahedron published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C12H20O6, Synthetic Route of 27943-46-0.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Torii, Sigeru’s team published research in Chemistry Letters in | CAS: 27943-46-0

Chemistry Letters published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C12H20O6, SDS of cas: 27943-46-0.

Torii, Sigeru published the artcileA facile hydroxymethylation of acetylene derivatives with paraformaldehyde by use of an electrogenerated base (EG base), SDS of cas: 27943-46-0, the publication is Chemistry Letters (1988), 1977-8, database is CAplus.

Electrolysis of a mixture of paraformaldehyde and terminal acetylene derivatives smoothly provided the corresponding hydroxymethylated compounds in high yields by passing less than 1 F/mol of electricity. Electroreduction of paraformaldehyde generated in situ an efficient base (EG base), which catalyzed hydroxymethylation of the acetylenes.

Chemistry Letters published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C12H20O6, SDS of cas: 27943-46-0.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Torii, Sigeru’s team published research in Tetrahedron Letters in 32 | CAS: 27943-46-0

Tetrahedron Letters published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C7H13Br, Formula: C10H16O2.

Torii, Sigeru published the artcilePalladium-catalyzed carbonylation to form 2-substituted 1,4-dihydro-4-oxoquinoline, Formula: C10H16O2, the publication is Tetrahedron Letters (1991), 32(2), 237-40, database is CAplus.

Palladium-catalyzed carbonylation of o-H2NC6H4R (R = Br, I) in the presence of R1CCH (R1 = alkyl, cyclohexyl, substituted Ph, benzodioxolyl) under proper conditions (20 kg cm-2 of CO at 120°) gave a variety of substituted dihydrooxoquinolines I in good yields.

Tetrahedron Letters published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C7H13Br, Formula: C10H16O2.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Ousji, Ons’s team published research in Chemical Research in Toxicology in 33 | CAS: 267244-08-6

Chemical Research in Toxicology published new progress about 267244-08-6. 267244-08-6 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Chiral,Carboxylic acid,Benzene,Phenol,Alcohol,Ether,, name is (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(4-(2-(4-hydroxyphenyl)propan-2-yl)phenoxy)tetrahydro-2H-pyran-2-carboxylic acid, and the molecular formula is C21H24O8, Related Products of tetrahydropyran.

Ousji, Ons published the artcileComprehensive In Vitro Metabolism Study of Bisphenol A Using Liquid Chromatography-High Resolution Tandem Mass Spectrometry, Related Products of tetrahydropyran, the publication is Chemical Research in Toxicology (2020), 33(6), 1468-1477, database is CAplus and MEDLINE.

Bisphenol A (BPA) metabolism has been investigated using several in vitro models, including human and rat liver microsomes and subcellular (S9) fractions, as well as human-recombinant cytochrome P 450 3A4 (CYP3A4) expressed in Supersomes, for a comprehensive look at all possible metabolic pathways. By an untargeted approach using liquid chromatog. coupled to a high-resolution quadrupole-time-of-flight mass spectrometer, we were able to detect a large number of known Phase I and Phase II metabolites of BPA, as well as several previously uncharacterized ones. A detailed fragmentation study of BPA and its detected metabolites was crucial to confirm structures. Isotope-labeled BPA analogs were highly useful for the structural elucidation of many metabolites. These results contribute to a better understanding of BPA metabolism, including pathways that may introduce addnl. toxicity, as well as help with the assessment of BPA exposure in different biol. matrixes.

Chemical Research in Toxicology published new progress about 267244-08-6. 267244-08-6 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Chiral,Carboxylic acid,Benzene,Phenol,Alcohol,Ether,, name is (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(4-(2-(4-hydroxyphenyl)propan-2-yl)phenoxy)tetrahydro-2H-pyran-2-carboxylic acid, and the molecular formula is C21H24O8, Related Products of tetrahydropyran.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Lee, Myung Sun’s team published research in Planta Medica in 68 | CAS: 69097-99-0

Planta Medica published new progress about 69097-99-0. 69097-99-0 belongs to tetrahydropyran, auxiliary class Other Aliphatic Heterocyclic,Benzene,Phenol,Ether,Inhibitor, name is 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, and the molecular formula is C16H14O6, Recommanded Product: 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one.

Lee, Myung Sun published the artcileInhibition of VHR dual-specificity protein tyrosine phosphatase activity by flavonoids isolated from Scutellaria baicalensis: structure-activity relationships, Recommanded Product: 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, the publication is Planta Medica (2002), 68(12), 1063-1065, database is CAplus and MEDLINE.

Three flavonoids: norwogonin, dihydronorwogonin and baicalein, were isolated from the roots of Scutellaria baicalensis, as potential inhibitors of VHR dual-specificity protein tyrosine phosphatase (DS-PTPase). Norwogonin (IC50 = 1.1μM), dihydronorwogonin (IC50 = 2.9μM) and baicalein (IC50 = 2.4μM) showed potent inhibitory activity toward VHR, but had no inhibitory activity against T-cell protein tyrosine phosphatase or serine/threonine protein phosphatase 1. From comparisons to the inhibitory activities of other similar flavonoids, it could be suggested that the presence of a hydroxy group in the B ring of flavonoids interferes with the inhibitory activity toward VHR DS-PTPase.

Planta Medica published new progress about 69097-99-0. 69097-99-0 belongs to tetrahydropyran, auxiliary class Other Aliphatic Heterocyclic,Benzene,Phenol,Ether,Inhibitor, name is 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, and the molecular formula is C16H14O6, Recommanded Product: 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Foster, G. L.’s team published research in Industrial and Engineering Chemistry in 51 | CAS: 27943-46-0

Industrial and Engineering Chemistry published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, Synthetic Route of 27943-46-0.

Foster, G. L. published the artcileAcetylenic corrosion inhibitors, Synthetic Route of 27943-46-0, the publication is Industrial and Engineering Chemistry (1959), 825-8, database is CAplus.

The mol. of propargyl alc. is systematically substituted and the corrosion inhibition of the resulting compounds is tested on AISI type 1020 mild steel in 10% HCl at 150°F. and in 15% HCl at 175 and 200°F. for 16 hrs., each solution containing 0.4% of the test substance. Of 39 compounds tested only iodopentynol ICCCMe2OH is a better inhibitor than propargyl alc. The exptl. results confirm the theory that the triple bond is the focal point of the inhibitory action against acid corrosion.

Industrial and Engineering Chemistry published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, Synthetic Route of 27943-46-0.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Van Snick, Wim’s team published research in Synthesis in | CAS: 27943-46-0

Synthesis published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C18H15N3O3, Recommanded Product: 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran.

Van Snick, Wim published the artcileA facile synthetic route towards substituted thieno[3,2-e]indoles, Recommanded Product: 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, the publication is Synthesis (2009), 767-774, database is CAplus.

A number of substituted thieno[3,2-e]indoles were prepared in high yields via a Bu4NF-mediated cyclization of 5-acetamido-4-ethynylbenzothiophenes, which, in turn, are easily accessible from the corresponding 4-iodobenzothiophenes. This method presents a viable alternative to the traditionally used Fischer indolization procedures.

Synthesis published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C18H15N3O3, Recommanded Product: 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Mori, Akihisa’s team published research in Phytochemistry in 27 | CAS: 69097-99-0

Phytochemistry published new progress about 69097-99-0. 69097-99-0 belongs to tetrahydropyran, auxiliary class Other Aliphatic Heterocyclic,Benzene,Phenol,Ether,Inhibitor, name is 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, and the molecular formula is C16H14O6, Recommanded Product: 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one.

Mori, Akihisa published the artcileCytotoxicity of plant flavonoids against HeLa cells, Recommanded Product: 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, the publication is Phytochemistry (1988), 27(4), 1017-20, database is CAplus.

(-)-Epigallocatechin and 28 other plant flavonoids were tested for cytotoxic activity against HeLa cells. Flavones and flavanones were active and several compounds with planar and non-planar ring systems showed high cytotoxic activities. Although no clear structure-activity relationship was deduced, hydroxyl groups on the A- and B-ring affected the cytotoxic potency pos. or neg., depending on the position of substitution. The uptake of thymidine was predominantly inhibited by myricetin, whereas the uptake of uridine was inhibited by (-)-epigallocatechin; the uptake of both thymidine and uridine were inhibited by 7,8-dihydroxyflavone.

Phytochemistry published new progress about 69097-99-0. 69097-99-0 belongs to tetrahydropyran, auxiliary class Other Aliphatic Heterocyclic,Benzene,Phenol,Ether,Inhibitor, name is 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, and the molecular formula is C16H14O6, Recommanded Product: 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics