(3-Carbethoxy-2-oxopropylidene)triphenylphosphorane. A reagent for [3+3] cyclohexenone annulation was written by Pietrusiewicz, K. Michal;Monkiewicz, Jaroslaw;Bodalski, Ryszard. And the article was included in Journal of Organic Chemistry in 1983.Application In Synthesis of 5,6-Dihydro-2H-pyran-3-carbaldehyde This article mentions the following:
Annulation of Ph3P:CHCOCH2CO2Et with α,β-unsaturated aldehydes R2CH:CR1CHO [R1 = H, R2 = H, Me, Ph; R1 = Me, R2 = H, Me; R1R2 = (CH2)3, CH2OCH2CH2, CH2CH2CH(CMe:CH2)CH2] gave 21-62% cyclohexanones I. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Application In Synthesis of 5,6-Dihydro-2H-pyran-3-carbaldehyde).
5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization. The most notable anticancer agent, bryostatin, and eribulin are marine macrolides having intriguing tetrahydropyran and furan motif. Application In Synthesis of 5,6-Dihydro-2H-pyran-3-carbaldehyde
Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics