Iridium-Catalyzed Enantioselective Hydrogenation of Unsaturated Heterocyclic Acids was written by Song, Song;Zhu, Shou-Fei;Pu, Liu-Yang;Zhou, Qi-Lin. And the article was included in Angewandte Chemie, International Edition in 2013.Category: tetrahydropyran This article mentions the following:
A variety of α,β-unsaturated heterocyclic carboxylic acids were hydrogenated with >90% enantiomeric excess using chiral spirophosphine oxazoline iridium complexes. The methodol. was applied the the preparation of γ-aminobutyric acid reuptake inhibitor (R)-tiagabine. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Category: tetrahydropyran).
5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are useful synthons for biologically important compounds. The most notable anticancer agent, bryostatin, and eribulin are marine macrolides having intriguing tetrahydropyran and furan motif. Category: tetrahydropyran
Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics