Addition of aldehydes to activated double bonds. XXVIII. Preparations and reactions of alkoxy and acetoxy 2,5-diketones was written by Stetter, Hermann;Mohrmann, Karl Heinrich;Schlenker, Walter. And the article was included in Chemische Berichte in 1981.Related Products of 13417-49-7 This article mentions the following:
Reaction of ROCH2CHO (R = Me, CHMe2, Bu, CH2Ph) with R1COCH:CH2 (R1 = Me, Et, Ph) gave ROCH2COCH2CH2COR1, which were cyclized to I or reacted with R2NH2 (R2 = Me, Ph) to give the pyrroles II. RCOCH2CH2COCH2OAc were obtained from RCHO and CH2:CHCOCH2OAc and were deacetylated to RCOCH2CH2COCH2OH. Treatment of CH2:CHCOR1 with R3CHO (R3 = 2,3-dihydro-4H-pyran-2-yl, 2,3-dihydro-6H-pyran-2-yl) gave R3COCH2CH2COR1 (R3 = tetrahydropyranyl). In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Related Products of 13417-49-7).
5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization. The bismuth chloride-assisted cross-cyclization between homoallylic alcohols and epoxides provided various benzyl tetrahydropyran derivatives. The reaction afforded good yields of desired products and occurred under mild conditions.Related Products of 13417-49-7
Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics