Moldoveanu, Serban C. et al. published their research in Beitraege zur Tabakforschung International in 2013 | CAS: 13417-49-7

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization. One classic procedure for the organic synthesis of tetrahydropyran is by hydrogenation of the 3,4-isomer of dihydropyran with Raney nickel.Quality Control of 5,6-Dihydro-2H-pyran-3-carbaldehyde

Formation of dihydroxybenzenes in cigarette smoke. part 2. contribution from quinic acid and myo-inositol was written by Moldoveanu, Serban C.;Davis, Michael F.. And the article was included in Beitraege zur Tabakforschung International in 2013.Quality Control of 5,6-Dihydro-2H-pyran-3-carbaldehyde This article mentions the following:

Formation of dihydroxybenzenes in cigarette smoke is a subject of considerable interest because some dihydroxybenzenes are co-carcinogens, (e.g., catechol and certain alkylcatechols), and others such as hydroquinone can form metabolites that have toxic or carcinogenic properties. This present study describes the contribution of tobacco quinic acid (or (1S,3R,4S,5R)-1,3,4,5-tetrahydroxycyclohexanecarboxylic acid) and myo-inositol (or (1R,2R,3S,4S,5R,6S)-cyclohexane-1,2,3,4,5,6-hexol) to the formation of dihydroxybenzenes in cigarette smoke. The study is a continuation of a previous one showing the contribution of chlorogenic acid and rutin as precursors for these compounds (6). The yields of dihydroxybenzenes formed by pyrolysis of quinic acid and myo-inositol are relatively high and both quinic acid and myo-inositol can be present in some tobacco types at levels as high as 1% by weight The level of these compounds makes them potentially important contributors to the formation of dihydroxybenzenes in cigarette smoke. Similar to the previous study on other dihydroxybenzene precursors from tobacco, this present study was done in three parts: (1) pyrolytic evaluation of the amount of dihydroxybenzenes in smoke generated from isolated quinic acid and myo-inositol; (2) anal. of smoke from cigarettes made from a variety of tobaccos (14 single grades) and two blended cigarettes, followed by correlations of dihydroxybenzene yields from these cigarettes with the level of quinic acid and myo-inositol in the tobaccos; (3) addition of quinic acid or myo-inositol to several tobaccos followed by the smoking of the spiked cigarettes and measurement of the dihydroxybenzenes yield increase. The study performed on a variety of single-grade tobacco cigarettes and for two blended-tobacco cigarettes (one being the 2R4F Kentucky reference) shows that the contribution of quinic acid and of inositol to the formation of catechol and hydroquinone in smoke depends on the blend, as previously shown for chlorogenic acid and rutin. The study results suggest that quinic acid and myo-inositol may be major contributors to the formation of dihydroxybenzenes in cigarette smoke. Although the calculations do not provide precise numbers for the contribution of quinic acid and inositol to the formation of dihydroxybenzenes, these results suggest that the contribution could be as high as 50 to 60% of the level of dihydroxybenzenes. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Quality Control of 5,6-Dihydro-2H-pyran-3-carbaldehyde).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization. One classic procedure for the organic synthesis of tetrahydropyran is by hydrogenation of the 3,4-isomer of dihydropyran with Raney nickel.Quality Control of 5,6-Dihydro-2H-pyran-3-carbaldehyde

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Marschall, Helga et al. published their research in Liebigs Annalen der Chemie in 1982 | CAS: 13417-49-7

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. In organic synthesis, the 2-tetrahydropyranyl group is used as a protecting group for alcohols. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.Reference of 13417-49-7

Synthesis of hydroxy-γ-lactones from α,β-unsaturated aldehydes was written by Marschall, Helga;Penninger, Josef;Weyerstahl, Peter. And the article was included in Liebigs Annalen der Chemie in 1982.Reference of 13417-49-7 This article mentions the following:

RCH:CR1CHO [I; R = Me, R1 = H; RR1 = (CH2)3-5, CH2CH2OCH2, CH2CH2CH2CMe2], Me2C:CHCHO (II), and III (R3 = CHO, R4R5 = bond) reacted in three steps (epoxidation, PO olefination, and selective hydrogenation to give the corresponding esters IV (R2 = CH2CH2CO2Et), IV (R = CH2CH2CO2Et, R1 = R2 = Me) and III (R3 = CH2CH2CO2Et, R4R5 = O). These steps were interchangeable, especially the epoxidation and olefination. These esters were hydrolyzed to give V [R6 = H, R7 = R8 = Me; R6R7 = (CH2)n, CH2OCH2CH2, R8 = H; R6R7 = CMe2CH2CH2CH2, R8 = Me; n = 4-5]. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Reference of 13417-49-7).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. In organic synthesis, the 2-tetrahydropyranyl group is used as a protecting group for alcohols. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.Reference of 13417-49-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Raftery, Monica M. et al. published their research in Fire Research Technical Paper (United Kingdom, Joint Fire Research Organization) in 1975 | CAS: 14431-43-7

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans and furans principally constitute as a central motif in diverse medicinally privileged molecules. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.Quality Control of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate

Explosibility tests for industrial dusts was written by Raftery, Monica M.. And the article was included in Fire Research Technical Paper (United Kingdom, Joint Fire Research Organization) in 1975.Quality Control of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate This article mentions the following:

Apparatus and procedures used for testing explosibility of industrial dust suspensions by the Fire Research Station are described. The min. ignition temperature, explosible concentration, and ignition energy and maximum explosion pressure, rate of pressure rise, and O concentration to prevent ignition are tabulated for 290 common industrial dusts, including metals, coal, foods, grain, paper, wood, rubbers, and plastics. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Quality Control of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans and furans principally constitute as a central motif in diverse medicinally privileged molecules. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.Quality Control of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Cabafi, Klara et al. published their research in Hemijska Industrija in 1973 | CAS: 14431-43-7

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyran is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuff. The reaction of tertiary 1,4- and 1,5-diols with cerium ammonium nitrate at room temperature gives tetrahydrofuran and tetrahydropyran derivatives in high yield and stereoselectivity. Various fragrant compounds have been synthesized using this method.Computed Properties of C6H14O7

Crrystallization of glucose. II. Effect of some parameters on crystallization of glucose monohydrate was written by Cabafi, Klara. And the article was included in Hemijska Industrija in 1973.Computed Properties of C6H14O7 This article mentions the following:

The optimum crystallization condition of D-glucose α-monohydrate [50-99-7] in the presence of acid enzymes was to start crystallization from a solution containing 70-1% anhydrous D-glucose and >5% seed crystals at 43-5.deg. initially and to cool at a rat of 0.3-0.4.deg./hr to 25-7.deg.. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Computed Properties of C6H14O7).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyran is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuff. The reaction of tertiary 1,4- and 1,5-diols with cerium ammonium nitrate at room temperature gives tetrahydrofuran and tetrahydropyran derivatives in high yield and stereoselectivity. Various fragrant compounds have been synthesized using this method.Computed Properties of C6H14O7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics