Allylation using allylborates was written by Hunter, Roger;Michael, Joseph P.;Tomlinson, Geoffrey D.. And the article was included in Tetrahedron in 1994.Computed Properties of C6H12O2 This article mentions the following:
The scope of allylations by organoborates was determined for a range of acetals activated by trimethylsilyl trifluoromethanesulfonate. Intermol. allylation of acyclic acetals proceeds smoothly and in high yield using lithium n-butyltriallylborate or lithium methyltriallylborate in THF at -78掳, while 1,3-dioxanes and dioxolanes give reduction products. Intramol. allylation may be carried out via anchoring the triallylborane using an alkoxide anion. Mechanistic studies indicate that allyl transfer is from boron and not silicon, while stereoselectivity studies on the crotylation of acyclic acetals as well as the allylation of chiral acetals derived from (2R,4R)-pentanediol indicate moderate levels fo diastereoselection. In the experiment, the researchers used many compounds, for example, 2-Methoxytetrahydro-2H-pyran (cas: 6581-66-4Computed Properties of C6H12O2).
2-Methoxytetrahydro-2H-pyran (cas: 6581-66-4) belongs to tetrahydropyran derivatives. Tetrahydropyran is a useful synthetic intermediate. Tetrahydropyranyl (THP-) ethers derived from the reaction of alcohols and dihydropyran are common intermediates in organic synthesis. Pyran derivatives such as pyran flavonoids are biologically important. Monosaccharides containing six-membered rings are called pyranose.Computed Properties of C6H12O2
Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics