A mild and efficient synthesis of chloro esters by cleavage of cyclic and acyclic ethers using Bi(NO3)3·5H2O as catalyst under solvent-free conditions was written by Suresh, V.;Suryakiran, N.;Venkateswarlu, Y.. And the article was included in Canadian Journal of Chemistry in 2007.Application In Synthesis of 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran This article mentions the following:
A facile, efficient synthesis of chloro esters is described. The reaction of cyclic and acyclic ethers with acid chlorides in the presence of catalytic amounts of Bi(NO3)3·5H2O under solvent-free conditions yielded the chloro esters, e.g., THF + AcCl → AcO(CH2)4Cl. Also, the catalyst can be recovered conveniently and reused efficiently at least six times. In the experiment, the researchers used many compounds, for example, 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5Application In Synthesis of 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran).
2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5) belongs to tetrahydropyran derivatives. Tetrahydropyran is a useful synthetic intermediate. Tetrahydropyranyl (THP-) ethers derived from the reaction of alcohols and dihydropyran are common intermediates in organic synthesis. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.Application In Synthesis of 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran
Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics