Month: February 2023

Tetrahydropyran esters as new attractants for cockroaches was written by Pandey, Karuna Shanker;Shriprakash;Rao, Karumuru Mallikarjuna;Vaidyanathaswamy, Ramamoorthy. And the article was included in Bioscience, Biotechnology, and Biochemistry in 1994.Recommanded Product: 103260-44-2 This article mentions the following:

Twenty four tetrahydropyran esters were synthesized and tested as attractants toward Blattella germanica and Supella longipalpa in the laboratory by using the choice-chamber method. In general, carboxylates were superior to propionates and acetates. Among the 2-, 3-, or 4-substituted esters, substitution at the 4-position was better than at the other two positions. These results are explained in terms of the receptor model proposed earlier by others. In the experiment, the researchers used many compounds, for example, Ethyl 2-(tetrahydro-2H-pyran-4-yl)acetate (cas: 103260-44-2Recommanded Product: 103260-44-2).

Ethyl 2-(tetrahydro-2H-pyran-4-yl)acetate (cas: 103260-44-2) belongs to tetrahydropyran derivatives. Tetrahydropyran is a useful synthetic intermediate. Tetrahydropyranyl (THP-) ethers derived from the reaction of alcohols and dihydropyran are common intermediates in organic synthesis. The bismuth chloride-assisted cross-cyclization between homoallylic alcohols and epoxides provided various benzyl tetrahydropyran derivatives. The reaction afforded good yields of desired products and occurred under mild conditions.Recommanded Product: 103260-44-2

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Synthesis of Bicyclic Tertiary α-Amino Acids was written by Strachan, Jon-Paul;Whitaker, Regina C.;Miller, Craig H.;Bhatti, Balwinder S.. And the article was included in Journal of Organic Chemistry in 2006.COA of Formula: C9H16O3 This article mentions the following:

Novel bicyclic α-amino acids, exo and endo-1-azabicyclo[2.2.1]heptane-2-carboxylic acid, 1-azabicyclo[2.2.1]heptane-7-carboxylic acid, and 1-azabicyclo[3.2.2]nonane-2-carboxylic acid were readily synthesized for the generation of neuronal nicotinic receptor ligands. Alkylation of glycine-derived Schiff bases, e.g. Ph₂C:NCH₂CO₂Me, or nitroacetates with cyclic ether electrophiles, e.g. 3-(iodomethyl)tetrahydrofuran, followed by acid-induced ring opening and cyclization in NH₄OH, allowed for the preparation of substantial quantities of the three tertiary bicyclic α-amino acids. In the experiment, the researchers used many compounds, for example, Ethyl 2-(tetrahydro-2H-pyran-4-yl)acetate (cas: 103260-44-2COA of Formula: C9H16O3).

Ethyl 2-(tetrahydro-2H-pyran-4-yl)acetate (cas: 103260-44-2) belongs to tetrahydropyran derivatives. Tetrahydropyran is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuff. The most notable anticancer agent, bryostatin, and eribulin are marine macrolides having intriguing tetrahydropyran and furan motif. COA of Formula: C9H16O3

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Kinetic modelling of the quality degradation of frozen watermelon tissue: effect of the osmotic dehydration as a pre-treatment was written by Dermesonlouoglou, Efimia;Giannakourou, Maria;Taoukis, Petros. And the article was included in International Journal of Food Science and Technology in 2007.Product Details of 14431-43-7 This article mentions the following:

Watermelon pieces were submitted to osmotic pre-treatment in alternative osmotic solutions of glucose, oligofructose and a high dextrose equivalent (DE) maltodextrin, in order to evaluate the quality and assess the stabilization accomplished during the subsequent frozen storage in a wide temperature range from -5 to -20 °C. Color change and total lycopene content loss were kinetically studied, and their temperature dependence was modelled by the Arrhenius equation. Dehydrofrozen samples exhibited significantly improved stability, with the rates of color change and total lycopene loss being reduced up to 70% and 38%, resp., for osmotically pre-treated watermelon, compared with the untreated samples. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Product Details of 14431-43-7).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are useful synthons for biologically important compounds. The most notable anticancer agent, bryostatin, and eribulin are marine macrolides having intriguing tetrahydropyran and furan motif. Product Details of 14431-43-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Fragment-Based Discovery of 5-Arylisatin-Based Inhibitors of Matrix Metalloproteinases 2 and 13 was written by Agamennone, Mariangela;Belov, Dmitry S.;Laghezza, Antonio;Ivanov, Vladimir N.;Novoselov, Anton M.;Andreev, Ivan A.;Ratmanova, Nina K.;Altieri, Andrea;Tortorella, Paolo;Kurkin, Alexander V.. And the article was included in ChemMedChem in 2016.Quality Control of 3-[(2-Tetrahydropyranyl)oxy]phenylboronic Acid This article mentions the following:

Matrix metalloproteinases (MMPs) are well-established targets for several pathologies. In particular, MMP-2 and MMP-13 play a prominent role in cancer progression. In this study, a structure-based screening campaign was applied to prioritize metalloproteinase-oriented fragments. This computational model was applied to a representative fragment set from the publicly available EDASA Scientific compound library. These fragments were prioritized, and the top-ranking hits were tested in a biol. assay to validate the model. Two scaffolds showed consistent activity in the assay, and the isatin-based compounds were the most interesting. These latter fragments have significant potential as tools for the design and realization of novel MMP inhibitors. In addition to their micromolar activity, the chem. synthesis affords flexible and creative access to their analogs. In the experiment, the researchers used many compounds, for example, 3-[(2-Tetrahydropyranyl)oxy]phenylboronic Acid (cas: 1287777-05-2Quality Control of 3-[(2-Tetrahydropyranyl)oxy]phenylboronic Acid).

3-[(2-Tetrahydropyranyl)oxy]phenylboronic Acid (cas: 1287777-05-2) belongs to tetrahydropyran derivatives. Tetrahydropyran is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuff. Pyran derivatives such as pyran flavonoids are biologically important. Monosaccharides containing six-membered rings are called pyranose.Quality Control of 3-[(2-Tetrahydropyranyl)oxy]phenylboronic Acid

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Kinetic studies on the loss of water from α-D-glucose monohydrate was written by Ponschke, Michelle A.;House, James E.. And the article was included in Carbohydrate Research in 2011.Recommanded Product: 14431-43-7 This article mentions the following:

Although the dehydration of α-D-glucose monohydrate is an important aspect of several industrial processes, there is uncertainty with regard to the applicable rate law and other factors that affect dehydration. Therefore, the dehydration of three glucose monohydrate samples has been studied using isothermal gravimetric anal. Dehydration follows a one-dimensional contraction (R1) rate law for the majority of kinetic runs, and an activation energy of 65.0 ± 3.9 kJ mol^-1 results when the rate constants are fitted to the Arrhenius equation. Fitting the rate constants to the Eyring equation results in values of 62.1 ± 3.7 kJ mol^-1 and -77.8 ± 4.7 J mol^-1 K^-1 for ΔH and ΔS, resp. The impedance effect on the loss of water vapor has also been investigated to determine the values for activation energy, enthalpy, and entropy for diffusion of water. The results obtained for the activation parameters are interpreted in terms of the absolute entropies of anhydrous glucose and the monohydrate. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Recommanded Product: 14431-43-7).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization. There is large number of marine macrolide natural products that contain tetrahydropyran and tetrahydrofuran ring together. For instance, goniodomin A (actin targeting polyether), prorocentrolide (toxin halistatins), and percentotoxineRecommanded Product: 14431-43-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Access to Fused Pyrroles from Cyclic 1,3-Dienyl Boronic Esters and Arylnitroso Compounds was written by Francois, Benjamin;Eberlin, Ludovic;Berree, Fabienne;Whiting, Andrew;Carboni, Bertrand. And the article was included in Journal of Organic Chemistry in 2020.Application of 13417-49-7 This article mentions the following:

Dienylboronates such as I were prepared by hydroboration of enynes with terminal alkyne moieties, by boron-Wittig reactions of bis(pinacolato)methane with enals, or by newly optimized tandem ring closing and olefin cross-metathesis and ring closing metathesis reactions of enynes or of triene II in the presence of the first- or second-generation Grubbs catalysts. Reaction of dienylboronates with aryl nitroso compounds RNO mediated by DBU in methanol yielded fused arylpyrroles such as III by a nitroso-Diels-Alder reaction followed by ring contraction. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Application of 13417-49-7).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. In organic synthesis, the 2-tetrahydropyranyl group is used as a protecting group for alcohols. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.Application of 13417-49-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Chiral Hetero- and Carbocyclic Compounds from the Asymmetric Hydrogenation of Cyclic Alkenes was written by Verendel, J. Johan;Li, Jia-Qi;Quan, Xu;Peters, Byron;Zhou, Taigang;Gautun, Odd R.;Govender, Thavendran;Andersson, Pher G.. And the article was included in Chemistry – A European Journal in 2012.COA of Formula: C6H8O2 This article mentions the following:

Several types of chiral hetero- and carbocyclic compounds have been synthesized by using the asym. hydrogenation of cyclic alkenes. N,P-Ligated iridium catalysts reduced six-membered cyclic alkenes, e.g., I, with various substituents and heterofunctionality in good to excellent enantioselectivity, whereas the reduction of five-membered cyclic alkenes, e.g., II, was generally less selective, giving modest enantiomeric excesses. The stereoselectivity of the hydrogenation depended more strongly on the substrate structure for the five- rather than the six-membered cyclic alkenes. The major enantiomer formed in the reduction of six-membered alkenes could be predicted from a selectivity model and isomeric alkenes had complementary enantioselectivity, giving opposite optical isomers upon hydrogenation. The utility of the reaction was demonstrated by using it as a key step in the preparation of chiral 1,3-cis-cyclohexane carboxylates. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7COA of Formula: C6H8O2).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyran is a useful synthetic intermediate. Tetrahydropyranyl (THP-) ethers derived from the reaction of alcohols and dihydropyran are common intermediates in organic synthesis. The reaction of tertiary 1,4- and 1,5-diols with cerium ammonium nitrate at room temperature gives tetrahydrofuran and tetrahydropyran derivatives in high yield and stereoselectivity. Various fragrant compounds have been synthesized using this method.COA of Formula: C6H8O2

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics