Month: February 2023

Takahashi, Shiro et al. published their research in Chemical & Pharmaceutical Bulletin in 1966 | CAS: 14431-43-7

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. In organic synthesis, the 2-tetrahydropyranyl group is used as a protecting group for alcohols. Pyran derivatives such as pyran flavonoids are biologically important. Monosaccharides containing six-membered rings are called pyranose.Recommanded Product: 14431-43-7

Benzimidazole N-oxides. VI. Reaction of 3-methoxy-l-methyl- and 1,2-dimethylbenzimidazolium iodide with various nucleophiles was written by Takahashi, Shiro;Kano, Hideo. And the article was included in Chemical & Pharmaceutical Bulletin in 1966.Recommanded Product: 14431-43-7 This article mentions the following:

The reactions of I with nucleophiles were considered to involve N-alkoxydihydro base intermediates II, but the high acidity of the C-2 proton suggested the possibility of a zwitter ion-carbene-type activated complex III. Both reaction pathways produced IV derivatives Evidence for the lability of the C-2 proton was shown by its rapid exchange with D and the low τ value (-1.00 in CDCl3) of the 2-proton signal. Reactions of I with KCN, NaOH, MeMgI, NaHSO3, NaOMe, iso-PrONa, NH2NH2, NH2Me, NH3, NHMe2, NH2Ph, HC(CN)CO2Me, H2C(CN)2, and NaBH4 were reported. Phys. constants of those compounds described with an elemental analysis were as follows: IV (B = OMe), m. 40-2°; IV (B = iso-PrO) isolated as picrate, m. 160° (decomposition); IV (B = iso-PrO) isolated as picrate, m. 160° (decomposition); IV (B = NHNH2), m. 242° (decomposition); IV (B = NHMe) (HI salt m. 275° (decomposition)), m. 185-6°; IV (B = NMe2) isolated as picrate, m. 191-2°; IV (B = NHPh).HI, m. 241-3° (decomposition); IV (B = CH(CN)2), m. >250°. Reactions of V with NaOH, MeONa, NH2NH2, NH3, NaHSO3, and NaBH4 gave VI [R = H (VII)] via abstraction of a proton from the 3-methoxyl group and loss of HCHO. V with KCN produced VII and VI [R = CN (VIII)], m. 210-11°, (the reaction in D2O gave VII and VIII having D incorporated in the C-2 Me group) through a reaction pathway involving abstraction of a 2-Me proton, followed by nucleophilic attack at C-6 and the concerted departure of methoxide ion. V, m. 150-1° (decomposition), was prepared by refluxing 1-methoxy-2-methylbenzimidazole (VIII) with excess MeI for 10 min., and VIII, m. 39-41°, was synthesized by heating a mixture of 1.5 g. 2-methylbenzimidazole 1-oxide, 10 ml. MeOH, 0.6 g. KOH, and 0.7 ml. MeI for 1 hr. at 50°. V heated in a sealed tube in CHCl3 at 100° for 4 hrs. produced 1,2,3-trimethylbenzimidazolium iodide, m. >250°. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Recommanded Product: 14431-43-7).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. In organic synthesis, the 2-tetrahydropyranyl group is used as a protecting group for alcohols. Pyran derivatives such as pyran flavonoids are biologically important. Monosaccharides containing six-membered rings are called pyranose.Recommanded Product: 14431-43-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Momany, F. A. et al. published their research in Carbohydrate Research in 2004 | CAS: 14431-43-7

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Dihydropyrans and tetrahydropyrans are examples of cyclic ethers widespread in nature. The reaction of tertiary 1,4- and 1,5-diols with cerium ammonium nitrate at room temperature gives tetrahydrofuran and tetrahydropyran derivatives in high yield and stereoselectivity. Various fragrant compounds have been synthesized using this method.Electric Literature of C6H14O7

B3LYP/6-311++G** study of monohydrates of α- and β-D-glucopyranose: hydrogen bonding, stress energies, and effect of hydration on internal coordinates was written by Momany, F. A.;Appell, M.;Strati, G.;Willett, J. L.. And the article was included in Carbohydrate Research in 2004.Electric Literature of C6H14O7 This article mentions the following:

Twenty-six monohydrates of α- and β-D-glucopyranose were studied using gradient methods at the B3LYP/6-311++G level of theory. Geometry optimization was carried out with the water mols. at different configurations around the glucose mol. A new nomenclature for hydrated carbohydrates was developed to describe the water configurations. Zero-point vibrational energy, enthalpy, entropy, and relative free energy were obtained using the harmonic approximation Hydrogen-bond energies for the monohydrates range from ∼-5 to -12 kcal/mol, and the average relative free energy is ∼5 kcal/mol. The 1-hydroxy position is the most energetically favored site for hydration, and the region between the two and three positions is the next-most favored site. A water mol. approaching α-D-glucose between the 1- and 2-hydroxy positions pulls the 2-hydroxyl hydrogen atom away from the 1-hydroxy oxygen atom, thus increasing the hydrogen-bond length and also increasing the α-D-glucose energy. The increase in energy that occurs with a similar interaction on the β-anomer is much less effective since the hydrogen bond is much longer. Using the calculated free energies of all 26 configurations, the anomer population (α/β) increases in the β-anomer population relative to the in vacuo case by ∼10% at the expense of the α-anomer, giving an (α/β) ratio of ∼50/50. This result arises from entropy contributions favoring the β-anomer more than the α-anomer. From anal. of donor and acceptor hydrogen-bond lengths, excellent correlation is found between the DFT calculated distances and those taken from carbohydrate structures in the Cambridge Crystallog. Data Bank. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Electric Literature of C6H14O7).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Dihydropyrans and tetrahydropyrans are examples of cyclic ethers widespread in nature. The reaction of tertiary 1,4- and 1,5-diols with cerium ammonium nitrate at room temperature gives tetrahydrofuran and tetrahydropyran derivatives in high yield and stereoselectivity. Various fragrant compounds have been synthesized using this method.Electric Literature of C6H14O7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Abagyan, G. V. et al. published their research in Khimicheskaya Fizika in 1994 | CAS: 14431-43-7

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate

Transformations of D-glucose in solid phase initiated by γ-irradiation was written by Abagyan, G. V.;Opresyan, A. S.. And the article was included in Khimicheskaya Fizika in 1994.Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate This article mentions the following:

The presence of water in γ-irradiated α-glucose leads to the appearance of primary free radicals of a new type without conformational inversion; conformational inversion is initiated by temperature in the absence of water and irradiation The presence of water in γ-irradiated β-glucose induces conformational inversion to α-glucose at high rate at 77 K. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Spreitzer, Helmut et al. published their research in Flavour and Fragrance Journal in 1995 | CAS: 13417-49-7

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyran is a useful synthetic intermediate. Tetrahydropyranyl (THP-) ethers derived from the reaction of alcohols and dihydropyran are common intermediates in organic synthesis. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.COA of Formula: C6H8O2

Synthesis and odor of bicyclo[2.2.2]octanone derivatives: β-hydroxy ketones and enones was written by Spreitzer, Helmut;Anderwald, Christian;Buchbauer, Gerhard. And the article was included in Flavour and Fragrance Journal in 1995.COA of Formula: C6H8O2 This article mentions the following:

β-Hydroxy ketones were prepared by aldol reaction of bicyclo[2.2.2]octan-2-one with various aldehydes . Dehydration of the ketols furnished the corresponding enones. The odor properties of these bicyclic, rigid hydroxy ketones as well as of the enones are described. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7COA of Formula: C6H8O2).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyran is a useful synthetic intermediate. Tetrahydropyranyl (THP-) ethers derived from the reaction of alcohols and dihydropyran are common intermediates in organic synthesis. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.COA of Formula: C6H8O2

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Corbett, E. C. et al. published their research in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy in 1991 | CAS: 14431-43-7

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Dihydropyrans and tetrahydropyrans are examples of cyclic ethers widespread in nature. One classic procedure for the organic synthesis of tetrahydropyran is by hydrogenation of the 3,4-isomer of dihydropyran with Raney nickel.Reference of 14431-43-7

Fourier transform Raman studies of materials and compounds of biological importance-II. The effect of moisture on the molecular structure of the alpha and beta anomers of D-glucose was written by Corbett, E. C.;Zichy, V.;Goral, J.;Passingham, C.. And the article was included in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy in 1991.Reference of 14431-43-7 This article mentions the following:

The effects of small amounts of water added to the alpha and beta anomers of D-glucose have been investigated. The monohydrate of α-D-glucose was formed under these conditions and its Fourier transform Raman spectrum has been recorded for the first time. The combination of crystallog. data and vibrational spectroscopy, based on the study of α- and β-D-glucose, with special emphasis on conformation and configuration sensitive modes, enabled band assignments to be made for the monohydrate of α-D-glucose. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Reference of 14431-43-7).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Dihydropyrans and tetrahydropyrans are examples of cyclic ethers widespread in nature. One classic procedure for the organic synthesis of tetrahydropyran is by hydrogenation of the 3,4-isomer of dihydropyran with Raney nickel.Reference of 14431-43-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Tamaru, Yoshinao et al. published their research in Journal of Organic Chemistry in 1988 | CAS: 13417-49-7

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Numerous natural products have tetrahydropyran skeleton as the building block for designing new natural products and their derivatives e.g. aplysiatoxins, avermectins, oscillatoxins, talaromycins, latrunculins and acutiphycins. Pyran derivatives such as pyran flavonoids are biologically important. Monosaccharides containing six-membered rings are called pyranose.Recommanded Product: 13417-49-7

Stereoselective intramolecular haloamidation of N-protected 3-hydroxy-4-pentenylamines and 4-hydroxy-5-hexenylamines was written by Tamaru, Yoshinao;Kawamura, Shinichi;Bando, Takashi;Tanaka, Kunitada;Hojo, Makoto;Yoshida, Zenichi. And the article was included in Journal of Organic Chemistry in 1988.Recommanded Product: 13417-49-7 This article mentions the following:

Haloamidation of N-(p-tolylsulfonyl)-3-hydroxy-4-pentenylamines proceeds regio- and stereoselectively to provide cis-2-(halomethyl)-3-hydroxypyrrolidines in high yields. The tosylamides with Ph and di-Me substituents at C-5 cyclize to give six-membered piperidine products. N-(Methoxycarbonyl)-3-hydroxy-4-pentenylamines undergo a similar cyclization to furnish cis-N-(methoxycarbonyl)-2-(halomethyl)-3-hydroxypyrrolidines, which further undergo a cyclization to give bicyclic oxazolidones (1-aza-3-oxabicyclo[3.3.0]octan-2-ones). The above reactions proceed in the dark, while the haloamidation of N-(p-tolylsulfonyl)-4-hydroxy-5-hexenylamine only proceeds upon exposure to ambient light and provides 2-(halomethyl)-3-hydroxypiperidine. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Recommanded Product: 13417-49-7).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Numerous natural products have tetrahydropyran skeleton as the building block for designing new natural products and their derivatives e.g. aplysiatoxins, avermectins, oscillatoxins, talaromycins, latrunculins and acutiphycins. Pyran derivatives such as pyran flavonoids are biologically important. Monosaccharides containing six-membered rings are called pyranose.Recommanded Product: 13417-49-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Albright, Thomas A. et al. published their research in Journal of Organic Chemistry in 1977 | CAS: 13417-49-7

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyran is a useful synthetic intermediate. Tetrahydropyranyl (THP-) ethers derived from the reaction of alcohols and dihydropyran are common intermediates in organic synthesis. There is large number of marine macrolide natural products that contain tetrahydropyran and tetrahydrofuran ring together. For instance, goniodomin A (actin targeting polyether), prorocentrolide (toxin halistatins), and percentotoxineRecommanded Product: 13417-49-7

Thermal rearrangement of α-oxo-α,β-unsaturated azines to N-substituted pyrazoles was written by Albright, Thomas A.;Evans, Steven;Kim, Choong S.;Labaw, Clifford S.;Russiello, Andrea B.;Schweizer, Edward E.. And the article was included in Journal of Organic Chemistry in 1977.Recommanded Product: 13417-49-7 This article mentions the following:

Thermolysis of α-oxo-α,β,-unsaturated azines R1COCR2:NN:CR3CR4:CHR5 [R1 = Me, Ph, EtO; R2 = H, Me, Ph; R3 = H, Me, Ph, CH:CHC6H4R6-4 (R6 = H, Cl), CH2P+Ph3Br-; R4 = H, Me, Br; R3R4 = (CH2)n (n = 3,4); R5 = Me, Ph, Bz, C6H4Cl-4, 2-furyl; R4R5 = (CH2)n (n = 3, 4), (CH2)3O, CH2O(CH2)2] is an efficient and general route to α-pyrazolyl esters or ketones I. The azines were prepared by either the condensation of α-diketone monohydrazones RCOC(:NNH2)R (R = Ph, Me) with α,β-unsaturatedaldehydes and ketones R1COCR2:CHR3 [R1 = H, Me, Ph; R2 = H, Me, Bz; R1R2 = (CH2)n (n = 3, 4); R3 = Me, Ph, Bz, 2-furyl; R2R3 = (CH2)n (n = 3, 4), (CH2)3O, CH2O(CH2)2] or the Wittig olefination of the stabilized phosphoranes Ph3P+C-HC(CH2R7):NN:CHCO2Et (R7 = H, P+Ph3Br-) with aldehydes 4-R8C6H4CHO (R8 = H, Cl). In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Recommanded Product: 13417-49-7).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyran is a useful synthetic intermediate. Tetrahydropyranyl (THP-) ethers derived from the reaction of alcohols and dihydropyran are common intermediates in organic synthesis. There is large number of marine macrolide natural products that contain tetrahydropyran and tetrahydrofuran ring together. For instance, goniodomin A (actin targeting polyether), prorocentrolide (toxin halistatins), and percentotoxineRecommanded Product: 13417-49-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Anonymous et al. published their research in Bollettino dei Chimici dell’Unione Italiana dei Laboratori Provinciali, Parte Scientifica in 1979 | CAS: 14431-43-7

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Dihydropyrans and tetrahydropyrans are examples of cyclic ethers widespread in nature. There is large number of marine macrolide natural products that contain tetrahydropyran and tetrahydrofuran ring together. For instance, goniodomin A (actin targeting polyether), prorocentrolide (toxin halistatins), and percentotoxineCategory: tetrahydropyran

Official methods of analysis. Analysis of sugars was written by Anonymous. And the article was included in Bollettino dei Chimici dell’Unione Italiana dei Laboratori Provinciali, Parte Scientifica in 1979.Category: tetrahydropyran This article mentions the following:

Official Italian methods of anal. for the determination of loss of weight on drying, dry matter, reducing sugars, ash, and optical rotation are given for table sugar [57-50-1], glucose syrup, glucose monohydrate [14431-43-7], anhydrous glucose [50-99-7], and other sugars for human consumption. The total dry weight is determined refractometrically, and the reducing sugars by the Knight and Allen, Luff and Schoorl, and Lane and Eynon methods. Ash is determined by calcination at 525° in the presence of dilute H2SO4. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Category: tetrahydropyran).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Dihydropyrans and tetrahydropyrans are examples of cyclic ethers widespread in nature. There is large number of marine macrolide natural products that contain tetrahydropyran and tetrahydrofuran ring together. For instance, goniodomin A (actin targeting polyether), prorocentrolide (toxin halistatins), and percentotoxineCategory: tetrahydropyran

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Muehlstaedt, Manfred et al. published their research in Journal fuer Praktische Chemie (Leipzig) in 1970 | CAS: 13417-49-7

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Dihydropyrans and tetrahydropyrans are examples of cyclic ethers widespread in nature. The most notable anticancer agent, bryostatin, and eribulin are marine macrolides having intriguing tetrahydropyran and furan motif. HPLC of Formula: 13417-49-7

Mechanisms of the synthesis of pyridine basis by the gas-phase reaction of α,β-unsaturated aldehydes and ammonia was written by Muehlstaedt, Manfred;Uebel, Hans J.;Moll, Karl K.. And the article was included in Journal fuer Praktische Chemie (Leipzig) in 1970.HPLC of Formula: 13417-49-7 This article mentions the following:

Comparison between the products of the gas-phase reaction of NH3 with acrolein (I), crotonaldehyde (II), 3-formyl-5,6-dihydro-2H-pyran (III), 3-formyl-2,6-dimethyl-5,6-dihydro-2H-pyran (IV) and 2-formyl-3,4-dihydro-2H-pyran (V), with the formation of pyridines, indicated that III, IV and V were not intermediates in the reaction of I and II. No diene and aldol reaction was involved in the dimerization of I and II prior to the pyridine formation. The dimerizations seem to occur by α-β addition The reaction of I gave pyridine (VI) and 3-methylpyridine (VII), that of II 4-methyl-3-ethylpyridine, that of III VII, that of IV 2-methyl-5-ethylpyridine, and that of V gave VI and VII. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7HPLC of Formula: 13417-49-7).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Dihydropyrans and tetrahydropyrans are examples of cyclic ethers widespread in nature. The most notable anticancer agent, bryostatin, and eribulin are marine macrolides having intriguing tetrahydropyran and furan motif. HPLC of Formula: 13417-49-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Fischer, Bernd M. et al. published their research in Proceedings of SPIE-The International Society for Optical Engineering in 2006 | CAS: 14431-43-7

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are useful synthons for biologically important compounds. The reaction of tertiary 1,4- and 1,5-diols with cerium ammonium nitrate at room temperature gives tetrahydrofuran and tetrahydropyran derivatives in high yield and stereoselectivity. Various fragrant compounds have been synthesized using this method.Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate

T-ray spectroscopy of biomolecules: from chemical recognition toward biochip analysis- horizons and hurdles was written by Fischer, Bernd M.;Helm, Hanspeter;Uhd Jepsen, Peter. And the article was included in Proceedings of SPIE-The International Society for Optical Engineering in 2006.Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate This article mentions the following:

In the recent years, there has been an increased interest in the exploitation of the far-IR spectral region for applications based on chem. recognition. The fact that on the one hand many packaging materials are transparent for THz radiation and on the other hand the THz-spectra of many pharmaceuticals, illicit drugs, and explosives show very specific fingerprints show the potential that THz spectroscopy holds for identification of concealed substances by comparing the spectral signatures with the entries in a database. Yet, due to the lack of appropriate techniques the far-IR region had for a long time be relatively unexplored, and therefore a detailed study of the far-IR spectra and the character of the mol. vibrations that give rise to the characteristic spectral signatures can help to evaluate the applicability of THz spectroscopy and imaging for quality control, chem. recognition and biomedical applications. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are useful synthons for biologically important compounds. The reaction of tertiary 1,4- and 1,5-diols with cerium ammonium nitrate at room temperature gives tetrahydrofuran and tetrahydropyran derivatives in high yield and stereoselectivity. Various fragrant compounds have been synthesized using this method.Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics