220641-87-2, N-Methyltetrahydro-2H-pyran-4-amine is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,220641-87-2
The mixture of 4-bromo-3-methoxybenzene-1-sulfonyl chloride (2-109, 180 mg, 0.63 mmol), K2C03 (174 mg, 1.26 mmol) and N-methyltetrahydro-2H-pyran-4-amine (73 mg, 0.63 mmol) in DCM (20 mL) was stirred at 40 C for 16 h. Upon reaction completion, the resulting mixture was filtered and then concentrated under reduced pressure to get title compound 2-118 (yellow solid, 210 mg, 91% yield). LCMS: 364 [M + HI .
The synthetic route of 220641-87-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE; GRAY, Nathanael S.; BUHRLAGE, Sara; ANDERSON, Kenneth; COTTINI, Francesca; TONON, Giovanni; (288 pag.)WO2016/161145; (2016); A1;,
Tetrahydropyran – Wikipedia
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