A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 33024-60-1, Name is Tetrahydro-2H-pyran-4-amine hydrochloride, molecular formula is C5H12ClNO. In a Patent£¬once mentioned of 33024-60-1, Application In Synthesis of Tetrahydro-2H-pyran-4-amine hydrochloride
PROGNOSTIC BIOMARKERS FOR TTK INHIBITOR CHEMOTHERAPY
The present invention provides a method for identifying a tumor – in a human individual or in an animal – that is susceptible to treatment with a TTK inhibitor, said method comprising: a] providing a sample of a tumor; b] determining the presence of a mutated CTNNB1 gene in said tumor sample, wherein said mutation is located in exon 3 of CTNNB1 and whereby the presence of a mutated CTNNB1 gene indicates that the tumor is susceptible to treatment with a TTK inhibitor. In an alternative aspect, step b] of the above defined method is replaced by the step of determining the presence of a mutated CTNNB1 protein in said tumor sample, wherein said mutation is located in exon 3 of CTNNB1 and whereby the presence of a mutated CTNNB1 protein indicates that the tumor is susceptible to treatment with a TTK inhibitor. In a further alternative, step b] comprises determining an altered expression of a CTNNB1 regulated gene, whereby an altered expression of a CTNNB1 regulated gene indicates that the tumor is susceptible to treatment with a TTK inhibitor.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Application In Synthesis of Tetrahydro-2H-pyran-4-amine hydrochloride, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 33024-60-1, in my other articles.
Reference£º
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics