624734-17-4, Name is 3-Methoxydihydro-2H-pyran-4(3H)-one, molecular formula is C6H10O3, belongs to Tetrahydropyrans compound, is a common compound. In a patnet, once mentioned the new application about 624734-17-4, Product Details of 624734-17-4
Novel 2-aminooctahydrocyclopentalene-3a-carboxamides as potent CCR2 antagonists
Novel CCR2 antagonists with a novel 2-aminooctahydrocyclopentalene-3a- carboxamide scaffold were designed. SAR studies led to a series of potent compounds. For example, compound 51 had a good PK profile in both dog and monkey, and exhibited excellent efficacy when dosed orally in an inflammation model in hCCR2 KI mice. In addition, an asymmetric synthesis to the core structures was developed.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Product Details of 624734-17-4. In my other articles, you can also check out more blogs about 624734-17-4
Reference£º
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics