220641-87-2, N-Methyltetrahydro-2H-pyran-4-amine is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
IV.2 (2, 2-Difluoro-propyl)-[5-(4,4, 5, 5-tetramethyl-[1, 3, 2]dioxaborolan-2-yl)- p rimidin-2-yl]-amine A mixture of 70 mg (0.29 mmol) 2-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2- yl)pyrimidine, 42 mg (0.32 mmol) 2,2-difluoro-propylamine hydrochloride, 0.13 ml (0.93 mmol) triethylamine and dioxane is heated to 90C for 1 h. After cooling to RT the reaction mixture is diluted with aqueous NaCI solution. The precipitate is filtered off, washed with water and dried . Yield: 1 10 mg (126%), ESI-MS: m/z = 218 (M+H)+, Rt(HPLC): 0.30 min (HPLC-B), 220641-87-2
220641-87-2 N-Methyltetrahydro-2H-pyran-4-amine 6991950, aTetrahydropyrans compound, is more and more widely used in various.
Reference£º
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BLUM, Andreas; GODBOUT, Cedrickx; HEHN, Joerg, P.; PETERS, Stefan; (74 pag.)WO2017/194453; (2017); A1;,
Tetrahydropyran – Wikipedia
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