Downstream synthetic route of 25637-16-5

25637-16-5, As the paragraph descriping shows that 25637-16-5 is playing an increasingly important role.

25637-16-5, 4-Bromotetrahydropyran is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

[00315] To 2.8h (30 mg, 0.079 mmol) and 4-bromotetrahydro-2H-pyran (91 mg , 0.552 mmol) in DMSO (Volume: 1 ml_), cesium carbonate (90 mg, 0.276 mmol) was added and stirred at 60 C for 2 hours or until done by LCMS. The crude solution containing the desired product 2.16a was taken to the next step, assume in quantitative yield, used as is. LC-MS (m/z): 465.4 [M+H]+, 0.89 min.

25637-16-5, As the paragraph descriping shows that 25637-16-5 is playing an increasingly important role.

Reference£º
Patent; NOVARTIS AG; FU, Jiping; KARUR, Subramanian; PFISTER, Keith Bruce; (110 pag.)WO2018/73753; (2018); A1;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics