31608-22-7, Name is 2-(4-Bromobutoxy)tetrahydro-2H-pyran, molecular formula is C9H17BrO2, belongs to Tetrahydropyrans compound, is a common compound. In a patnet, once mentioned the new application about 31608-22-7, Application In Synthesis of 2-(4-Bromobutoxy)tetrahydro-2H-pyran
Synthesis of Some Bioactive Acetylenic Alcohols, Components of the Marine Sponge Cribrochalina vasculum
Grignard coupling of isopropylmagnesium bromide with 4-(tetrahydropyranyloxy)bromobutane (2) and subsequent bromination gave 4.Alkylation of 1-(tetrahydropyranyloxy)undec-10-yne (5) with 4 and 1-bromohexane, acidic hydrolysis, and bromination furnished 7 and 9, respectively.Likewise, coupling of isobutylmagnesium bromide with 12-(tetrahydropyranyloxy)bromododecane (12) followed by bromination afforded 14.Alkylation of 1-(tetrahydropyranyloxy)-2-propyne (15) with 7, 9, and 14 and oxidation of the respective products afforded the alkynals 16a-c.These on reaction with lithium acetylide and subsequent chemoselective trans reduction of the internal alkynes led to the target compounds I-III.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application In Synthesis of 2-(4-Bromobutoxy)tetrahydro-2H-pyran. In my other articles, you can also check out more blogs about 31608-22-7
Reference£º
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics