Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Category: Tetrahydropyrans, 108-55-4, Name is Dihydro-2H-pyran-2,6(3H)-dione, molecular formula is C5H6O3, belongs to Tetrahydropyrans compound. In a document, author is Ozbek, Sevgi Sarigul, introduce the new discover.
Axially chiral hemiaminals from nonracemic alpha-amino acid derivatives (thiohydantoins): Synthesis and isomer identification
Stable, nonracemic axially chiral hemiaminals (O,N-hemiacetals) have been synthesized stereoselectively from lithium aluminum hydride (LiAlH4) reductions of nonracemic 5-methyl- and 5-isopropyl-3-(o-aryl)-2-thioydantoins in tetrahydrofuran (THF) at room temperature in 10 min. PredominantlyS-configured hemiaminals at C-4 of the heterocyclic ring were produced from the S-configured thiohydantoins at C-5 (by 80% when the C5 substituent is methyl and by 97% when it is isopropyl). The configuration at C-5 was retained during the reduction reaction. The stereochemical outcome of the axially chiral hemiaminals resulted from their conformational preferences.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 108-55-4. Category: Tetrahydropyrans.
Reference:
Tetrahydropyran – Wikipedia,
,Tetrahydropyran – an overview | ScienceDirect Topics