Final Thoughts on Chemistry for 2,3,4,6-Tetra-o-acetyl-D-glucopyranose

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Esterase catalyzed regioselective hydrolyses of acetylated monosaccharides

Deacylations of fully acylated D-glucopyranoses, methyl D-glucopyranosides, 2-acetamido-2-deoxy-D-glucopyranoses glucopyranoses and methyl 2-acetamido-2-deoxy-D-glucopyranosides catalyzed by rabbit serum or the esterase isolated from rabbit serum were investigated. Depending on the structure of the acyl protecting group a high degree of regioselectivity is observed. Products of enzymic hydrolysis followed by intramolecular migrations of acetyl groups are also described.

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Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics