With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.101691-94-5,4-(Iodomethyl)tetrahydro-2H-pyran,as a common compound, the synthetic route is as follows.
To carbazole (111 mg, 0.66 mmol) was added 4-(iodomethyl)tetrahydro-2H- pyran (150 mg, 0.66 mmol), sodium hydride (60% in mineral oil, 27 mg, 0.8 mmol), and dimethylsulfoxide. After 9 days, the mixture was placed on silica and purified by flash chromatography (15 % ethyl acetate, 85 % hexanes) to yield the title compound (24 mg, 14 %)., 101691-94-5
The synthetic route of 101691-94-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; IMMUSOL INCORPORATED; WO2008/21745; (2008); A2;,
Tetrahydropyran – Wikipedia
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