With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.185815-59-2,4-Isobutyldihydro-2H-pyran-2,6(3H)-dione,as a common compound, the synthetic route is as follows.
Step 4, dilute 3-isobutylglutaric anhydride with methyl tert-butyl ether, add 100 ml of 10% ammonia water in a 500 ml reaction flask, and cool the mixture of 3-isobutylglutaric anhydride after cooling. 80 ml of tert-butyl ether solution, the reaction was stirred at room temperature, and the organic phase was separated, and the pH was adjusted to 0.5-1 with 6 mol/L hydrochloric acid. Washing, decoloring, suction filtration, washing with water, and drying were carried out to obtain (¡À)- 3-carbamoylmethyl-5-methylhexanoic acid;, 185815-59-2
As the paragraph descriping shows that 185815-59-2 is playing an increasingly important role.
Reference£º
Patent; Anhui Dongkai Biological Technology Co., Ltd.; Liu Yaopeng; Yu Zhenyun; Zhou Zhongwei; Wan Qing; Lu Jun; Fu Xuelian; (6 pag.)CN110156732; (2019); A;,
Tetrahydropyran – Wikipedia
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