Application of 14215-68-0, Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.14215-68-0, Name is N-((2S,3R,4R,5R,6R)-2,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide, molecular formula is C8H15NO6. In a patent, introducing its new discovery.
The hydroxy protons of unsaturated di-, tetra-, hexa- and octa-saccharides of hyaluronan (DeltaHA2, DeltaHA4, DeltaHA 6 and DeltaHA8) in 85% H2O/15% acetone-d 6 have been studied by NMR spectroscopy. The chemical shifts (delta), chemical shift differences (Deltadelta), temperature coefficients (ddelta/dT) and nuclear or rotating-frame Overhauser effects (NOEs or ROEs) of hydroxy protons were measured to gain insight into hydration, hydrogen bonds and flexibility of the HA structure. The NMR data give the first experimental evidence that weak hydrogen bonds exist between O(4)H of N-acetyl-D-glucosamine (GlcNAc) and O(5) of D-glucuronic acid (GlcA) across the beta(1?3) glycosidic linkage and between O(3)H of GlcA and O(5) of GlcNAc across the beta(1?4)-linkage. A chemical exchange was observed between O(4)H of GlcNAc and O(2)H of GlcA over the beta(1?3)-linkage. The interaction could be mediated through water bridge(s) and thus contribute to the water-retaining ability of hyaluronan. In this study it was also demonstrated how the chemical shifts of exchangeable hydroxy or amide proton signals can be used to describe small structural and conformational perturbations within large oligosaccharides.
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Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics