29943-42-8, Dihydro-2H-pyran-4(3H)-one is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Intermediate 11 : 2-(Tetrahydro-2H-pyran-4-yl)-lH-imidazole-5-carbaldehydeStep a: tetrahydro-2H-pyran-4-carbonitrile[0473] A solution of dihydro-2H-pyran-4(3H)-one (10.0 g, 0.1 mol) and TosMIC (25.35 g, 0.13 mol) in DME (75.0 mL) was cooled to -10C and t-BuOK (28.0 g, 0.25 mol) was added in portions to keep the temperature below 5C. The reaction mixture was stirred at 0C for 1 h and then at room temperature for 2 h. The solvent was removed under reduced pressure and the residue was treated with water. The resulting mixture was extracted with ether and the combined organic layers were washed with brine, dried over anhydrous Na2S04 and concentrated. The residue was purified by distillation to affordl8 g of the title compound as a light yellow liquid (73% yield).
As the paragraph descriping shows that 29943-42-8 is playing an increasingly important role.
Reference£º
Patent; ZENOBIA THERAPEUTICS, INC.; BOUNAUD, Pierre-Yves; NIENABER, Vicki; STEENSMA, Ruo, W.; LOWE, John, A., III; WO2012/178015; (2012); A2;,
Tetrahydropyran – Wikipedia
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