14774-37-9, Tetrahydropyran-4-methanol is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Intermediate 86: Tetrahvdro-2H-pyran-4-ylmethyl methanesulfonateTo tetrahydro-2H-pyran-4-ylmethanol (6.2g) in dry dichloromethane (226.3 ml) at O0C and under nitrogen, was added triethylamine (18.1 ml), followed by mesyl chloride (5.4 ml). The reaction was allowed to warm to room temperature and left at this temperature overnight. The reaction mixture was washed with saturated aqueous sodium bicarbonate (200 ml). The organic layer was separated, passed through a hydrophobic frit to dry and concentrated in vacuo to yield a light brown lumpy solid (10.17 g).1H NMR (DMSO): delta 4.06 (2H, d), 3.85 (2H, m), 3.35-3.25 (1 H, m), 3.17 (3H, s), 2.50 (1 H, m), 2.00-1.87 (1 H, m), 1.58 (2H, m), 1.32-1.20 (2H, m)., 14774-37-9
The synthetic route of 14774-37-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; SMITHKLINE BEECHAM CORPORATION; WO2008/101867; (2008); A1;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics