Application In Synthesis of 2-Chloro-1,3-bis(2,6-diisopropylphenyl)-1H-imidazol-3-ium chloride. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 2-Chloro-1,3-bis(2,6-diisopropylphenyl)-1H-imidazol-3-ium chloride, is researched, Molecular C27H36Cl2N2, CAS is 1228185-09-8, about One-step synthesis of [18F]fluoro-4-(vinylsulfonyl)benzene: A thiol reactive synthon for selective radiofluorination of peptides. Author is Ma, Gaoyuan; McDaniel, James W.; Murphy, Jennifer M..
Radiolabeled peptide-based mol. imaging probes exploit the advantages of large biologics and small mols., providing both exquisite selectivity and favorable pharmacokinetic properties. Here, we report an operationally simple and broadly applicable approach for the 18F-fluorination of unprotected peptides via a new radiosynthon, [18F]fluoro-4-(vinylsulfonyl)benzene. This reagent demonstrates excellent chemoselectivity at the cysteine residue and rapid 18F-labeling of a diverse scope of peptides to generate stable thioether constructs.
If you want to learn more about this compound(2-Chloro-1,3-bis(2,6-diisopropylphenyl)-1H-imidazol-3-ium chloride)Application In Synthesis of 2-Chloro-1,3-bis(2,6-diisopropylphenyl)-1H-imidazol-3-ium chloride, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1228185-09-8).
Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics