Brief introduction of 137052-08-5

As the paragraph descriping shows that 137052-08-5 is playing an increasingly important role.

137052-08-5, 1-(Tetrahydro-2H-pyran-4-yl)ethanone is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Example 16. Synthesis of 3-fluoro-2-(5-oxo-4-(3-(tetrahydro-2H-pyran-4-yl)-lH- razol- l-yl)-6,7-dihydro-5H-pyrrolo [3,4-b] pyridin-2-yl)benzonitrile, I- 16 16.4 1-16 Synthesis of compound 16.2. Solution of 16.1 (0.5g, 3.9mmol, leq) in DMF-DMA (5 niL) was heated to 100 C for 16h. Upon completion of the reaction was reaction, solvents were removed under reduced pressure to get crude 16.2 (0.45g, 62.95%), MS(ES): m/z 184.12 [M+H]+. The crude product was used in to next step without further purification., 137052-08-5

As the paragraph descriping shows that 137052-08-5 is playing an increasingly important role.

Reference£º
Patent; NIMBUS LAKSHMI, INC.; MASSE, Craig E.; GREENWOOD, Jeremy Robert; ROMERO, Donna L.; HARRIMAN, Geraldine C.; WESTER, Ronald T.; SHELLEY, Mee; KENNEDY-SMITH, Joshua Jahmil; DAHLGREN, Markus; MONDAL, Sayan; (342 pag.)WO2017/40757; (2017); A1;,
Tetrahydropyran – Wikipedia
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