So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Brenstrum, Tim; Gerristma, David A.; Adjabeng, George M.; Frampton, Christopher S.; Britten, James; Robertson, Alan J.; McNulty, James; Capretta, Alfredo researched the compound: 1,3,5,7-Tetramethyl-6-phenyl-2,4,8-trioxa-6-phosphaadamantane( cas:97739-46-3 ).Application In Synthesis of 1,3,5,7-Tetramethyl-6-phenyl-2,4,8-trioxa-6-phosphaadamantane.They published the article 《Phosphaadamantanes as Ligands for Palladium Catalyzed Cross-Coupling Chemistry: Library Synthesis, Characterization, and Screening in the Suzuki Coupling of Alkyl Halides and Tosylates Containing β-Hydrogens with Boronic Acids and Alkylboranes》 about this compound( cas:97739-46-3 ) in Journal of Organic Chemistry. Keywords: phosphaadamantane ligand preparation Suzuki coupling catalyst. We’ll tell you more about this compound (cas:97739-46-3).
A 15-member library of phosphaadamantane ligands has been prepared via P-arylation of 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phosphaadamantane. Screening of this tertiary phosphine collection has allowed for the rapid determination of the most suitable ligand, specifically 1,3,5,7-tetramethyl-6-(2,4-dimethoxyphenyl)-2,4,8-trioxa-6-phosphaadamantane, for facilitating Suzuki-type couplings of alkyl halides or tosylates containing β-hydrogens with either boronic acids or alkylboranes.
There is still a lot of research devoted to this compound(SMILES：CC1(C2)OC(C3)(C)OC2(C)OC3(C)P1C4=CC=CC=C4)Application In Synthesis of 1,3,5,7-Tetramethyl-6-phenyl-2,4,8-trioxa-6-phosphaadamantane, and with the development of science, more effects of this compound(97739-46-3) can be discovered.
Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics