The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 1-Bromo-2-pentyne( cas:16400-32-1 ) is researched.Name: 1-Bromo-2-pentyne.Veltri, Lucia; Amuso, Roberta; Cuocci, Corrado; Vitale, Paola; Gabriele, Bartolo published the article 《Palladium-Catalyzed Cyclocarbonylation Approach to Thiadiazafluorenones: A Correction》 about this compound( cas:16400-32-1 ) in Journal of Organic Chemistry. Keywords: benzimidazolothiazinone preparation; palladium catalyst cyclocarbonylation benzimidazolyl propargyl thioether; revision structure methylbenzimidazolothiazinone. Let’s learn more about this compound (cas:16400-32-1).
In the presence of PdI2 using KI2, CO, and O2 in MeOH, benzimidazolyl propargyl thioethers with internal alkyne moieties such as I underwent cyclocarbonylation reaction to yield 2-methyl-3-substituted thiadiazafluorenones (benzimidazolothiazinones) such as II. The structures of II and of two other benzimidazolothiazinones were determined by X-ray crystallog. A correction is provided to rectify the previous erroneous assignment of the position of the Me group in the thiadiazafluorenones; the previous products were formed as the 2-Me thiadiazafluorenones and not as the 3-Me thiadiazafluorenones.
From this literature《Palladium-Catalyzed Cyclocarbonylation Approach to Thiadiazafluorenones: A Correction》,we know some information about this compound(16400-32-1)Name: 1-Bromo-2-pentyne, but this is not all information, there are many literatures related to this compound(16400-32-1).
Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics