The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《One-Pot Oxidative C-H Activation/Aza-Prins-Type Reaction of Tertiary Alkynylamines: A Counter Ion-Induced Iminium Ion-Alkyne Cyclization》. Authors are Orejarena Pacheco, Julio Cesar; Pusch, Stefan; Geske, Leander; Opatz, Till.The article about the compound:1-Bromo-2-pentynecas:16400-32-1,SMILESS:CCC#CCBr).Recommanded Product: 16400-32-1. Through the article, more information about this compound (cas:16400-32-1) is conveyed.
Herein, the design and development of a new one-pot and metal-free oxidative C-H activation/aza-Prins type cyclization of alkynylamines was reported. The scope of this method was demonstrated by the preparation of ten new pyrido[2,1-a]isoquinolines I [R1 = R2 = H, OMe; R3 = H, Ph, 2-thienyl, etc.; R4 = H, Et; stereo = cis, trans] in moderate to high yields (38-92%). Furthermore, a mechanistic proposal for the alkyne aza-Prins cyclization was described based on DFT calculations
Compound(16400-32-1)Recommanded Product: 16400-32-1 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(1-Bromo-2-pentyne), if you are interested, you can check out my other related articles.
Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics