Simple exploration of 125552-89-8

125552-89-8, The synthetic route of 125552-89-8 has been constantly updated, and we look forward to future research findings.

125552-89-8, 4-(Bromomethyl)tetrahydropyran is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a stirred solution of 8d (370mg, 2.52mmol) in anhydrous DMF (5mL) cooled to O0C, was added 60% NaH (121mg, 3.02mmol) slowly. The resulting mixture was stirred at O0C for Ih, was then added 4-(bromomethyl) -2H-3,4,5,6- tetrahydropyran (25a) (496g, 2.77mmol). The resulting mixture was then heated at 6O0C overnight. After being evaporated, the mixture was purified by column chromatography (PE:EA=10:l) to provide 25b (541mg, 87.6%).

125552-89-8, The synthetic route of 125552-89-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; XCOVERY, INC.; WO2008/88881; (2008); A1;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics