In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Direct conversion of (R)-epichlorohydrin to (S)-3-aminopropane-1,2-diol: an important chiral C-3 building block, published in 2011-12-31, which mentions a compound: 82954-65-2, mainly applied to aminopropanediol asym synthesis, Category: tetrahydropyran.
A new and effective method for the preparation of (S)-3-amino-1,2-propanediol was established starting from (R)-epichlorohydrin. The synthetic approach involves the reaction of (R)-epichlorohydrin with acetone catalyzed by BF3·OEt2 to give (R)-4-(chloromethyl)-2,2-dimethyl-1,3-dioxolane. Subsequent replacement of the Cl with NH2 group by azidation followed by reduction gave ((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methanamine, which was converted into (S)-3-aminopropane-1,2-diol·HCl by acetal deprotection with MeOH·HCl.
Compounds in my other articles are similar to this one((S)-(2,2-dimethyl-[1,3]-dioxolan-4-yl)-methylamine)Category: tetrahydropyran, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.
Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics