Category: tetrahydropyran. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 1-Bromo-2-pentyne, is researched, Molecular C5H7Br, CAS is 16400-32-1, about Synthesis of Functionalized Cyclobutane-Fused Naphthalene Derivatives via Cascade Reactions of Allenynes with tert-Butyl Nitrite. Author is Feng, Tian; He, Yan; Zhang, Xinying; Fan, Xuesen.
A novel synthesis of cyclobutanol-fused 2-nitronaphthalen-1-ols I [R1 = H, 6-Cl, 7-Me, 7-OCH3; R2 = Ph, 4-ClC6H4, thiophen-3-yl, etc.] and nitrocyclobutane-fused naphthalene-1,2-diones II [R3 = H, Et, C(O)OC2H5; R4 = H, Cl, F, OCH3; R5 = H, F, OCH3, Me; R6 = H; R5R6 = -CH=CH-CH=CH-] through cascade reactions of benzene-linked allenynes 2-(CCR2)-3-(R6)-4-(R5)-5-(R4)-C6HC(O)CH=C=CHR3 with tert-Bu nitrite is presented. The formation of the title compounds I and II involves a tandem process including allenyne [2+2] cycloaddition, radical addition onto the in situ formed cyclobutenyl moiety followed by radical coupling/oxidation Interestingly, different kinds of functionalized naphthalene derivatives could be obtained selectively from the same substrates, and the selectivity was easily controlled by finely tuning the reaction conditions.
Although many compounds look similar to this compound(16400-32-1)Category: tetrahydropyran, numerous studies have shown that this compound(SMILES:CCC#CCBr), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics