Ros, Oihana published the artcileSimultaneous enzymatic hydrolysis and extraction of endocrine-disrupting chemicals in fish bile using polyethersulfone polymer, Formula: C21H24O8, the publication is Analytical and Bioanalytical Chemistry (2015), 407(24), 7413-7423, database is CAplus and MEDLINE.
This study describes a new method for the simultaneous extraction and enzymic hydrolysis of alkylphenols, estrogens, bisphenol-A and phthalate metabolite (mono-2-ethylhexyl ester, MEHP) in fish bile using polyethersulfone (PES) polymer as sorptive material. Parameters affecting the hydrolysis (enzyme amount) and extraction (nature of polymeric material, PES desorption solvent nature and time, PES amount and time profile) were optimized. The optimum conditions were fixed as: 5 PES tubes (1.5 cm length × 0.7 mm o.d.) were added to a vessel with 100 μL of sample, 800 μL of ultrapure water, 1.5 mL phosphate buffer (0.1 mol L-1, pH 6) and 200 μL of β-glucuronidase (1000 U mL-1) enzyme and the mixture was stirred at 37 °C and 550 rpm for 3 h. Quant. results were obtained after desorption of PES material using 500 μL of Et acetate. The extracts were reconstituted in 250 μL of methanol and analyzed by liquid chromatog.-tandem mass spectrometry, obtaining apparent recoveries in the range of 73-134 % using deuterated compounds surrogates corrections. Relative standard deviations below 27 % were obtained for all target analytes and the method detection limits (MDLs) were in low nanograms per mL level for all the studied compounds, except in the case of MEHP which was detected at higher concentration levels (ng μL-1) in bile samples that do not allow its MDL determination Bisphenol A (MDL-10.8 ng mL-1), diethylstilbestrol (MDL-1.4 ng mL-1) and MEHP (975-2604 ng mL-1) were detected in gray mullets captured nearby the wastewater treatment plant of Gernika (Biosphere Reserve of Urdaibai).
Analytical and Bioanalytical Chemistry published new progress about 267244-08-6. 267244-08-6 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Chiral,Carboxylic acid,Benzene,Phenol,Alcohol,Ether,, name is (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(4-(2-(4-hydroxyphenyl)propan-2-yl)phenoxy)tetrahydro-2H-pyran-2-carboxylic acid, and the molecular formula is C21H24O8, Formula: C21H24O8.
Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics