Hirano, Yutaka published the artcileSteroid studies. 77. Synthesis of (22R- and (22S)-22,25-dihydroxyvitamin D3 and determination of their biological activity, Name: 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, the publication is Chemical & Pharmaceutical Bulletin (1981), 29(8), 2254-60, database is CAplus and MEDLINE.
Bisnorcholenal 3-tetrahydropyranyl ether was coupled with the lithium acetylide derived from 2-methyl-3-butyn-2-ol tetrahydropyranyl ether to give a 74% yield of a 1:1 mixture of the cholest-5-ene-3β,22,25-trihydroxy-23-yne 3,25-bis(tetrahydropyranyl)ethers. After resolution of the C-22 epimers and determination of their configurations, both isomers were converted into 22,25-dihydroxycholesterol 3,22-diacetates and into 25-hydroxy-22-methoxycholesterol 3-acetates. These compounds were converted to (22R)- and (22S)-22,25-dihydroxyvitamin D3 and to 25-hydroxy-22-methoxyvitamin D3. Biol. activity of these vitamin D3 derivatives were determined
Chemical & Pharmaceutical Bulletin published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, Name: 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran.
Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics