Le Pham, Ngoc Son’s team published research in Journal of Organic Chemistry in 85 | CAS: 27943-46-0

Journal of Organic Chemistry published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, HPLC of Formula: 27943-46-0.

Le Pham, Ngoc Son published the artcileOxidative Dehydrosulfurative Cross-Coupling of 3,4-Dihydropyrimidine-2-thiones with Alkynes for Access to 2-Alkynylpyrimidines, HPLC of Formula: 27943-46-0, the publication is Journal of Organic Chemistry (2020), 85(7), 5087-5096, database is CAplus and MEDLINE.

Dihydropyrimidinethiones such as I [R = t-Bu, Me(CH2)n, i-PrCH2CH2, PhCH2CH2, c-C6H11CH2, cyclopentyl, cyclohexyl, PhCH2O(CH2)3, THPOCMe2, Ph, 4-MeC6H4, 4-MeOC6H4, 1-naphthyl; n = 5, 7; THP = tetrahydro-2-pyranyl] underwent desulfurative Sonogashira coupling and oxidative aromatization reactions with terminal alkynes RCCH in the presence of Pd(OAc)2, 1,3-bis(diphenylphosphino)propane (dppp), copper(I) 2-thiophenecarboxylate (CuTC), and Cs2CO3 in 4:1 toluene:MeCN to yield alkynylpyrimidines such as II [R = t-Bu, Me(CH2)n, i-PrCH2CH2, PhCH2CH2, c-C6H11CH2, cyclopentyl, cyclohexyl, PhCH2O(CH2)3, THPOCMe2, Ph, 4-MeC6H4, 4-MeOC6H4, 1-naphthyl; n = 5, 7].

Journal of Organic Chemistry published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, HPLC of Formula: 27943-46-0.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics