Thermodynamic and kinetic studies of glucose mutarotation by using a portable personal blood glucose meter was written by Perles, Carlos Eduardo;Volpe, Pedro Luiz Onofrio. And the article was included in Acta Chimica Slovenica in 2009.Safety of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate This article mentions the following:
A thermodn. and kinetic study of the mutarotation reaction of D-glucose in aqueous solution was carried out using a portable personal blood glucose meter. This phys. chem. experiment is proposed as an alternative to classical polarimetry. The glucose meter allows the indirect monitoring of the mutarotation process in water, by using an enzymic redox reaction. The test strips of the glucose meter contain glucose dehydrogenase which converts β-D-glucose into D-glucolactone. This reaction selectively converts glucose and generates an elec. current in the glucose meter which is proportional to the glucose concentration This experiment allows the teacher to explore the kinetics and thermodn. of the mutarotation of D-glucose and, moreover, the stereospecificity of enzymic reactions. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Safety of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate).
(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are useful synthons for biologically important compounds. The most notable anticancer agent, bryostatin, and eribulin are marine macrolides having intriguing tetrahydropyran and furan motif. Safety of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate
Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics