Synthesis and odor of bicyclo[2.2.2]octanone derivatives: β-hydroxy ketones and enones was written by Spreitzer, Helmut;Anderwald, Christian;Buchbauer, Gerhard. And the article was included in Flavour and Fragrance Journal in 1995.COA of Formula: C6H8O2 This article mentions the following:
β-Hydroxy ketones were prepared by aldol reaction of bicyclo[2.2.2]octan-2-one with various aldehydes . Dehydration of the ketols furnished the corresponding enones. The odor properties of these bicyclic, rigid hydroxy ketones as well as of the enones are described. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7COA of Formula: C6H8O2).
5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyran is a useful synthetic intermediate. Tetrahydropyranyl (THP-) ethers derived from the reaction of alcohols and dihydropyran are common intermediates in organic synthesis. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.COA of Formula: C6H8O2
Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics