Watanabe, Atsushi et al. published their research in Yakugaku Zasshi in 2002 | CAS: 14431-43-7

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans and furans principally constitute as a central motif in diverse medicinally privileged molecules. The reaction of tertiary 1,4- and 1,5-diols with cerium ammonium nitrate at room temperature gives tetrahydrofuran and tetrahydropyran derivatives in high yield and stereoselectivity. Various fragrant compounds have been synthesized using this method.Category: tetrahydropyran

Study of crystalline drugs by means of a polarizing microscope. XIX. A trial production of a table of the optical crystallographic characteristics of crystalline drugs including crystal habits was written by Watanabe, Atsushi. And the article was included in Yakugaku Zasshi in 2002.Category: tetrahydropyran This article mentions the following:

It was clarified in previous report that the predominant faces of crystal habits mainly coincide with the morphol. crystal face at (001), (010), or (100), and therefore the two measurable key refractive indexes are closely related to the principal sections of the two axial wave surfaces and coincide with the one or two of the three principal refractive indexes. The three principal refractive indexes of biaxial crystalline drugs were measured and tabulated in the “General Information” section of the National Formulary compiled by the American Pharmaceutical Association A series of studies was conducted to measure the key refractive indexes of the crystalline drugs listed in the Japanese Pharmacopoeia X or XI so that the data could be used to improve the quant. anal. of their crystal habits. The purpose of the present study was to examine data on both the key and principal refractive indexes and attempt to produce a general authorized table of optic crystallog. characteristics, including crystal habits, for simpler and more reliable polarizing microscopy studies. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Category: tetrahydropyran).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans and furans principally constitute as a central motif in diverse medicinally privileged molecules. The reaction of tertiary 1,4- and 1,5-diols with cerium ammonium nitrate at room temperature gives tetrahydrofuran and tetrahydropyran derivatives in high yield and stereoselectivity. Various fragrant compounds have been synthesized using this method.Category: tetrahydropyran

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics