Tetrahydropyranylation of alcohols and phenols using copper 4-aminobenzenesulfonate and acetic acid as a catalyst system was written by Song, Zhi-guo;Liu, Lian-li;Gao, Jing-jing;Wang, Min. And the article was included in Huaxue Yanjiu Yu Yingyong in 2012.Application In Synthesis of 2-Methoxytetrahydro-2H-pyran This article mentions the following:
A synergistic catalytic effect between metal 4-aminobenzenesulfonates(Cu, Ni, Zn, Co, Al, Cd, Mn, La, Ce(III), Pr, Nd, Sm, Eu, Tb, Dy, Ho, Er) and Bronsted acid in tetrahydropyranylation of alcs. and phenols was investigated. The catalytic system, combined copper 4-aminobenzenesulfonate with acetic acid, proved to be very active. Various alcs. and phenols were tetrahydropyranylated in high yields at room temperature without solvent. After reaction, copper 4-aminobenzenesulfonate could be recycled at least six times without significant loss of activity. In the experiment, the researchers used many compounds, for example, 2-Methoxytetrahydro-2H-pyran (cas: 6581-66-4Application In Synthesis of 2-Methoxytetrahydro-2H-pyran).
2-Methoxytetrahydro-2H-pyran (cas: 6581-66-4) belongs to tetrahydropyran derivatives. Dihydropyrans and tetrahydropyrans are examples of cyclic ethers widespread in nature. One classic procedure for the organic synthesis of tetrahydropyran is by hydrogenation of the 3,4-isomer of dihydropyran with Raney nickel.Application In Synthesis of 2-Methoxytetrahydro-2H-pyran
Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics