A Photocatalyzed Cascade Approach Toward the Tetracyclic Core of Akuammiline Alkaloids was written by Wang, Qile;Hu, Jie;Zheng, Nan. And the article was included in Organic Letters in 2019.HPLC of Formula: 40365-61-5 This article mentions the following:
A cascade approach toward the tetracyclic core (e.g. I) of akuammiline alkaloids which features high modularity and convergence is reported. Distinct substitution pattern can be readily introduced to the tetracyclic core by varying three building blocks with similar complexity. The critical event in the cascade is a regio- and stereoselective 1,2-shift enabled by a carbocation that sets up the core. In the experiment, the researchers used many compounds, for example, 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5HPLC of Formula: 40365-61-5).
2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5) belongs to tetrahydropyran derivatives. Numerous natural products have tetrahydropyran skeleton as the building block for designing new natural products and their derivatives e.g. aplysiatoxins, avermectins, oscillatoxins, talaromycins, latrunculins and acutiphycins. The reaction of tertiary 1,4- and 1,5-diols with cerium ammonium nitrate at room temperature gives tetrahydrofuran and tetrahydropyran derivatives in high yield and stereoselectivity. Various fragrant compounds have been synthesized using this method.HPLC of Formula: 40365-61-5
Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics