Wang, Chang-Wei et al. published their research in Journal of the American Chemical Society in 2011 | CAS: 6581-66-4

2-Methoxytetrahydro-2H-pyran (cas: 6581-66-4) belongs to tetrahydropyran derivatives. Tetrahydropyran is a useful synthetic intermediate. Tetrahydropyranyl (THP-) ethers derived from the reaction of alcohols and dihydropyran are common intermediates in organic synthesis. Pyran derivatives such as pyran flavonoids are biologically important. Monosaccharides containing six-membered rings are called pyranose.Recommanded Product: 6581-66-4

Sensing or No Sensing: Can the Anomeric Effect Be Probed by a Sensing Molecule? was written by Wang, Chang-Wei;Ying, Fu-Ming;Wu, Wei;Mo, Yi-Rong. And the article was included in Journal of the American Chemical Society in 2011.Recommanded Product: 6581-66-4 This article mentions the following:

The anomeric effect plays a central role in carbohydrate chem., but its origin is controversial, and both the hyperconjugation model and the electrostatic model have been proposed to explain this phenomenon. Recently, Cocinero et al. designed a peptide sensor, which can bind to a sugar mol. Me D-galactose, and claimed that the anomeric effect can be sensed by the spectral changes from the β- to the α-complex, which are ultimately attributed to the lone pair electron d. change on the endocyclic oxygen atom. Here, we provide strong computational evidence showing that the observed spectral changes simply come from the conformational differences between the α- and β-anomers, as the replacement of the endocyclic oxygen atom with a methylene group, which disables both the endo- and the exo-anomeric effects in Me D-galactose, leads to similar spectral shifts. In other words, the “sensor” cannot probe the anomeric effect as claimed. We further conducted detailed energetic and structural analyses to support our arguments. In the experiment, the researchers used many compounds, for example, 2-Methoxytetrahydro-2H-pyran (cas: 6581-66-4Recommanded Product: 6581-66-4).

2-Methoxytetrahydro-2H-pyran (cas: 6581-66-4) belongs to tetrahydropyran derivatives. Tetrahydropyran is a useful synthetic intermediate. Tetrahydropyranyl (THP-) ethers derived from the reaction of alcohols and dihydropyran are common intermediates in organic synthesis. Pyran derivatives such as pyran flavonoids are biologically important. Monosaccharides containing six-membered rings are called pyranose.Recommanded Product: 6581-66-4

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics