Synthesis and hypotensive activity of a series of 2-substituted 5,6-dimethoxyindazoles was written by Schwan, Thomas J.;Honkomp, LeRoy J.;Davis, Charles S.;Lougheed, Guy S.. And the article was included in Journal of Pharmaceutical Sciences in 1978.Recommanded Product: 2-(Aminomethyl)tetrahydropyran This article mentions the following:
The synthesis and hypotensive activity in the dog of a series of 2-substituted 5,6-dimethoxyindazoles (e.g. I) are reported. Structure-activity relationships for this class of compounds are discussed. Indazoles containing the diethylaminoethyl, 3-pyridyl, and hydroxyethyl functions in the 2-position were the most effective in lowering blood pressure for the longest times (>270 min). In the experiment, the researchers used many compounds, for example, 2-(Aminomethyl)tetrahydropyran (cas: 6628-83-7Recommanded Product: 2-(Aminomethyl)tetrahydropyran).
2-(Aminomethyl)tetrahydropyran (cas: 6628-83-7) belongs to tetrahydropyran derivatives. Tetrahydropyran is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuff. One classic procedure for the organic synthesis of tetrahydropyran is by hydrogenation of the 3,4-isomer of dihydropyran with Raney nickel.Recommanded Product: 2-(Aminomethyl)tetrahydropyran
Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics