Stereoselective Total Synthesis of Rugulactone was written by Das, Biswanath;Srinivas, Yallamalla;Sudhakar, Chithaluri;Reddy, Parigi Raghavendar. And the article was included in Helvetica Chimica Acta in 2011.Recommanded Product: 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran This article mentions the following:
The stereoselective synthesis of the naturally occurring dihydropyranone rugulactone (I) has been accomplished starting from 3-phenylpropan-1-ol employing Maruoka allylation and ring-closing metathesis as the key steps. In the experiment, the researchers used many compounds, for example, 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5Recommanded Product: 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran).
2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5) belongs to tetrahydropyran derivatives. Dihydropyrans and tetrahydropyrans are examples of cyclic ethers widespread in nature. There is large number of marine macrolide natural products that contain tetrahydropyran and tetrahydrofuran ring together. For instance, goniodomin A (actin targeting polyether), prorocentrolide (toxin halistatins), and percentotoxineRecommanded Product: 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran
Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics