5631-96-9, 2-(2-Chloroethoxy)tetrahydro-2H-pyran is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
5631-96-9, 2,3-Dicyanohydroquinone (10.0 g, 0.062 mol), K2CO3 (19.0 g, 0.137 mol), chloride 1 (22.6 g , 0.137 mol), and KI (100 mg) in 200 mL DMF were stirred at 60 C for 48 h, when additional chloride 1 (11.3 g, 0.068 mol, 1.1 equiv) was added. After 48 h, the mixture was poured onto ice (500 g) and filtered to yield a beige solid, which was recrystallized from MeOH to yield dinitrile 2 (14.8 g, 57 %) as a white crystalline solid: IR (neat) numax 2940, 2231 cm-1; 1H NMR (500 MHz, CDCl3) delta 1.54 – 1.80 (m, 12H), 3.53 – 4.28 (m, 12H), 4.71 (br s, 2H), 7.28 (s, 2H); 13C NMR (125 MHz, CDCl3) delta 155.5, 119.1, 113.1, 105.7, 99.4, 70.0, 65.6, 62.5, 30.6, 25.4, 19.5; MALDI-MS calcd. for C22H28N2NaO6: [M + Na]+ 439.5, found: 439.6; ESI-MS calcd. for C44H56N4NaO12: [2M + Na]+ 855.4, found: 854.9. ESI-HRMS calcd. for C22H28N2NaO6: [M + Na]+ 439.184, found: 439.1844; calcd. for C44H56N4NaO12: [2M + Na]+ 855.3787, found: 855.3786.
As the paragraph descriping shows that 5631-96-9 is playing an increasingly important role.
Reference£º
Article; Trivedi, Evan R.; Blumenfeld, Carl M.; Wielgos, Todd; Pokropinski, Sharon; Dande, Prasad; Hai, Ton T.; Barrett, Anthony G.M.; Hoffman, Brian M.; Tetrahedron Letters; vol. 53; 41; (2012); p. 5475 – 5478;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics