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Green synthesis of 1,4-disubstituted-1,2,3-triazoles via click reaction using nano magnetic Fe3O4 core decorated with cyclodextrin-citric acid (Fe3O4@CD-CIT) acting as a phase transfer nanoreactor with low copper loading under ultrasonication at 40 C, in aqueous media is described. Anchoring the surface of magnetite with cyclodextrin (CD) prevents its agglomeration and at the same time, CD provides a hydrophobic niche for lipophilic reactants while its outer hydrophilic core makes the reaction feasible in water yielding almost quantitative yield of desired products. Magnetic separation using an external magnet, recyclability and reuse (7 times), without appreciably affecting the %yield of the products are its other attractive attributes. Gram scale synthesis was also achieved with 93% yield.

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Tetrahydropyran – Wikipedia,
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Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. In homogeneous catalysis, catalysts are in the same phase as the reactants.10343-06-3, C14H20O10. A document type is Article, introducing its new discovery., name: 2,3,4,6-Tetra-o-acetyl-D-glucopyranose

Analogs of naturally occurring furanones that were reported to be weak inhibitors of Serratia marcescens chitinases were prepared and tested towards various chitinases. Some of these compounds – but not the natural products – were found to be weak but selective inhibitors; all glycosylated analogs tested were inactive. Activation of the plant enzyme hevamine was observed in one case, which is unusual. Georg Thieme Verlag Stuttgart.

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Trichloroisocyanuric acid (TCCA), an inexpensive, commercially available, and non-toxic reagent has been used for the activation of thioglycosides toward their hydrolysis to the corresponding hemiacetals in high to excellent yields. The methodology provides a mild reaction condition for dealing with compounds containing acid sensitive functional groups.

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A lipid-coated beta-D-galactosidase could act as an efficient catalyst for transgalactosylation in the water-organic two phases: both the hydrophobic lipid-coated enzyme and alcohols were solubilized in isopropyl ether and mixed with an aqueous solution of lactose (a galactosyl donor). When a native beta-D-galactosidase was employed for the same reaction, neither the transgalactosylation nor the hydrolysis reaction proceeded due to the deactivation of the enzyme at the interface.

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Reaction of (-) 2-tert-butyl-2-methyl-1,3-benzodioxole-4-carboxylic acid with per-O-acetyl-D- and L-glucopyranosyl bromides yielded diastereomeric per-O-acetylated glycopyranosyl 2-tert-butyl-2-methyl-1,3-benzodiazole-4-carboxylates. Their 1H-n.m.r. signals, especially the strong singlet peaks of tert-Bu and Me groups in the 1-ester portion were diagnostic for the determination of the D,L-configuration and optical purity of monosaccharides. Reaction of (-)2-tert-butyl-2-methyl-1,3-benzodioxole-4-carboxylic acid with per-O-acetyl-D-and L-glucopyranosyl bromides yielded diastereomeric per-O-acetylated glycopyranosyl 2-tert-butyl-2-methyl-1, 3-benzodiazole-4-carboxylates. Their H-n.m.r. signals, especially the strong singlet peaks of tert-bu and Me groups in the 1-ester portion were diagnostic for the determination of the D,L-configuration and optical purity of monosaccharides.

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A variety of thioglycosides are chemoselectively hydrolyzed to the corresponding 1-hydroxy glycosides using equimolar amounts of NIS/TFA as promoter systems.

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Chemistry is a science major with cience and engineering. The main research directions are chemical synthesis, new energy materials, preparation and modification of special coatings, and research on the structure and performance of functional materials10343-06-3, Name is 2,3,4,6-Tetra-o-acetyl-D-glucopyranose, molecular formula is C14H20O10. In a Article,once mentioned of 10343-06-3, Reference of 10343-06-3

Vaccines play a primary role in the protection of human health by preventing infectious and chronic diseases. Recently we have reported 1,2-O-distearoyl-3-O-beta-D-sulfoquinovosylglycerol (beta-SQDG18), here named Sulfavant A (1), which shows promising properties as a new molecular adjuvant in in vitro and in vivo tests. In the present manuscript, we provide full details about a synthetic strategy for the preparation of 1, including a discussion of chemical determinants of the activity and the major technical hurdles we faced during the study. Synthesis of Sulfavant A (1) is achieved by a versatile procedure based on a trichloroacetimidate methodology and peracetate sugar precursors. The final design opens possibilities for the preparation of a series of interesting analogs for further pharmacological optimization and development, including derivatives containing different saturated and polyunsaturated fatty acids (e.g., 17 and 22).

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Anomeric O-arylation and O-hctarylation of tetra-O-bcnzyl-, tetra-O-acctyl-, and O-unprotected glucose (1a-c) can be directly performed with electron dcficienl aromatic and hctcroaromatic systems having fluoro- (2A-2F) or phenylsulfonyl (3B, 3G-3K), respectively, as leaving groups. The reactions were carried out in DMF as solvent at room temperature with NaH as the base; they led in the products 4 to an exchange of the leaving group by the glucopyranosyloxy moicly; mainly beta-products were obtained.

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Various thioglycosides 1 are smoothly hydrolyzed chemo-selectively to the corresponding 1-hydroxy sugars 2 in good yields at 0-5C by employing (NH4)6Mo7O24· 4H2O-H2O2 or H2MoO4·H2O-H2O2 to promote oxidation of ammonium bromide in the presence of perchloric acid in CH2Cl2-H2O solvent system. Mild conditions, good yields, no side reactions such as bromination either at the anomeric position or double bond, and even oxidation at the sulfur are some of the major advantages.

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Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps. 10343-06-3, Name is 2,3,4,6-Tetra-o-acetyl-D-glucopyranose, molecular formula is C14H20O10. In a Article,once mentioned of 10343-06-3, Safety of 2,3,4,6-Tetra-o-acetyl-D-glucopyranose

Glucosylquestiomycin, a novel N-glucopyranoside of questiomycin A, was isolated from the culture broth of Microbispora sp. TP-A0184. The absolute configuration of the sugar was determined as D-configuration by chemical synthesis. The new antibiotic showed antibacterial activity against Gram-positive and -negative bacteria and yeasts and cytotoxic activity against U937 cells.

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