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A series of novel acetylated piperazine-containing N-glucosides and bis(N-glucoside) 8a-i were synthesized by the nucleophilic addition of acetylated glucopyranosyl isothiocyanate with various substituted piperazines in THF with high yields. Their novel deacetylated products 9a-i were also synthesized after Me-ONa/MeOH treatment. The preliminary bioassays for 18 novel title compounds showed that several compounds have significant fungicidal activity against Fusarium omysporum, Cercospora arachidicola and Phytophthora capsici at 50 mug/mL.

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Tetrahydropyran – Wikipedia,
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The presence of base-hydrolyzable conjugates of abscisic acid metabolites in fruit was examined using HPLC.Among the fruits investigated, avocado (Persia americana) was shown to contain a new conjugate of dihydrophaseic acid.The conjugate was identified as dihydrophaseic acid-4′-O-beta-glucoside.

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Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. In homogeneous catalysis, catalysts are in the same phase as the reactants.10343-06-3, C14H20O10. A document type is Article, introducing its new discovery., Computed Properties of C14H20O10

Two dinuclear DyIII complexes, [Dy2(hmb)2(OTf)2(H2O)4]?HOTf?2 THF (A?HOTf?2 THF) and [Dy2(hmi)3(H2O)2]?2 HOTf (B?2 HOTf), have been synthesized by the reaction of Dy(OTf)3 and the Schiff-base ligands H2hmb (N?-(2-hydroxy-3-methoxybenzylidene)benzohydrazide) or H2hmi ((2-hydroxy-3-methoxyphenyl)methylene isonicotinohydrazine). Disarmed glycosyl trichloroacetimidates can be activated by complex A in the synthesis of 1,2-trans-glycosides with primary and secondary acceptors. This method offers an efficient route to selectively deacetylated monosaccharides and disaccharides in high yields and a green catalyst that can be easily recycled and reused.

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Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

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The use of the tertiary base 1,4-diazabicyclo<2,2,2>octane, together with 1-fluoro-2,4-dinitrobenzene in the solvent DMF, proved to be an efficient method for the introduction of the 2,4-dinitrophenyl (DNP) group at different positions, including the anomeric centre of glucose and galactose.The introduction of the DNP ethers at the anomeric centre leads exclusively to the formation of beta-DNP ethers.The latter derivatives can be easily converted with potassium carbonate in DMF into the alpha-DNP ethers.The X-ray analysis of 2,4-dinitrophenyl-2,3,4,6-tetra-O-acetyl-alpha-D-glucopyranoside is discused.The DNP group can also be used as a protective group in the synthesis of a disaccharide (i.e. 8 and as a UV probe to monitor (254 nm) and analyse (HPLC) sugar intermediates.

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Tetrahydropyran – Wikipedia,
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Palladium(0)-catalyzed reaction of various carbohydrates derived from glucofuranose, mannofuranose, ribofuranose, glucopyranose, and glucosamine, beating a free hydroxyl group, with 1,4-bis-(methoxycarbonyloxy)but-2-ene afforded the corresponding bis-glycosides of butene-1,4-diol. Hydrogenation in the presence of palladium on charcoal of these unsaturated compounds led to the formation of the bis-glycosides of butane-1,4-diol. The condensation was successfully extended to the bis-carbonate of 1,2-bis-[(1-hydroxy)propen-2-yl]benzene and derivatives of glucofuranose, ribofuranose and glucosamine.

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Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

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Glycosyl ortho-alkynylbenzoates have emerged as a new generation of donors for glycosidation under the catalysis of gold(I) complexes such as Ph 3PAuOTf and Ph3PAuNTf2 (Tf= trifluoromethanesulfonate). A wide variety of these donors, including 2-deoxy sugar and sialyl donors, are easily prepared and shelf stable. The glycosidic coupling yields with alcohols are gener-ally excellent; even direct coupling with the poorly nucleophilic amides gives satisfactory yields. Moreover, excellent alpha-selective glycosylation with a 2-deoxy sugar donor and beta-selective sialylation have been realized. Application of the present glycosylation protocol in the efficient synthesis of a cyclic triterpene tetrasaccharide have further demonstrated the versatility and efficacy of this new method, in that a novel chemoselective glycosylation of the carboxylic acid and a new one-pot sequential glycosylation sequence have been implemented.

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Tetrahydropyran – Wikipedia,
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A simple and mild method for regioselective anomeric deacetylation of peracetylated glycopyranoses using copper(II) acetate dihydrate and methanol/water (9:1) is described.

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Tetrbutylammonium salts strongly influence the stereoselectivity of O-anomeric alkylation and allows to shift from beta to alpha selectivity. Allyl glucosaminide 7 prepared in this way, was used to synthesize die new type of C2 symmetric neoglycoconjugates 1a-c.

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Penta-O-acetyl-alpha-D-Glucopyranose was selectively deacetylated in aqueous media by lipases from Candida cilindracea (CCL) adsorbed on octyl- agarose support. Enzymatic hydrolyses was regioselective at the 4-position under neutral pH and towards the 6 position under acidic conditions. This enzymatic approach allows the one step synthesis of 1,2,3,6-tetra-O-acetyl- alpha-D-glucopyranoses 1, a useful intermediate in oligosaccharide synthesis.

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lodonium ion (NIS/TfOH, cat.) assisted glycosylation of a sugar acceptor with properly protected enthyl(phenyl)-2-O-phenoxythiocarbonyl 1-thio-beta-D-gluco- or 1-thio-alpha-D-mannopyranoside donors gives the respective 1,2-trans linked 2?-ethyl(phenyl)thio-2?-deoxy-alpha-D-manno- or beta-D-glucopyranosides.

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