Reference of 14215-68-0, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 14215-68-0, Name is N-((2S,3R,4R,5R,6R)-2,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide, molecular formula is C8H15NO6. In a Article£¬once mentioned of 14215-68-0
The carbohydrate-binding properties of Castanea crenata agglutinin (CCA) were investigated by an enzyme-linked lectin absorbent assay. The binding ability of each carbohydrate was compared using IC50 values. CCA exhibited mannose/glucose specificity, as observed with many mannose-binding jacalin-related lectins. For oligosaccharides containing glucose, it has been shown that the degree of polymerization and the linkage mode of glucose residues have no effect on CCA-carbohydrate interaction; thus, only the non-reducing end glucose unit in glucooligosaccharides may be involved in the interaction with CCA. Among mannooligosaccharides, CCA strongly recognized alpha-(1?3)-d- Man-[alpha-d-Man-(1?6)]-d-Man, which is a core in N-linked carbohydrate chains. By considering the results with glycoproteins, it is likely that CCA binds preferentially to mono- or non-sialylated biantennary carbohydrate chains. We also obtained Kd values by analysis of the dependency of the IC50 on CCA concentration, based on the hypothesis that CCA has a single binding site or two equivalent binding sites. The estimated Kd values for mannose, glucose and alpha-(1?3)-d-Man-[alpha-d-Man- (1?6)]-d-Man were 2.39, 7.19 and 0.483 mM, respectively. The relative binding abilities showed good agreement with the relative inhibition intensities. Isothermal calorimetric titration was carried out to directly estimate the dissociation constants of CCA for mannose and for alpha-d-Man-(1?3)-d-Man. The values were 2.34 mM for mannose and 0.507 mM alpha-d-Man-(1?3)-d-Man. These results suggest that the relative inhibition intensity represents the ratio of Kd values and that CCA has a single or two equivalent binding sites.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 14215-68-0 is helpful to your research., Reference of 14215-68-0
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Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics