Category: 40365-61-5

Stereoselective Total Synthesis of Rugulactone was written by Das, Biswanath;Srinivas, Yallamalla;Sudhakar, Chithaluri;Reddy, Parigi Raghavendar. And the article was included in Helvetica Chimica Acta in 2011.Recommanded Product: 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran This article mentions the following:

The stereoselective synthesis of the naturally occurring dihydropyranone rugulactone (I) has been accomplished starting from 3-phenylpropan-1-ol employing Maruoka allylation and ring-closing metathesis as the key steps. In the experiment, the researchers used many compounds, for example, 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5Recommanded Product: 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran).

2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5) belongs to tetrahydropyran derivatives. Dihydropyrans and tetrahydropyrans are examples of cyclic ethers widespread in nature. There is large number of marine macrolide natural products that contain tetrahydropyran and tetrahydrofuran ring together. For instance, goniodomin A (actin targeting polyether), prorocentrolide (toxin halistatins), and percentotoxineRecommanded Product: 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Bidentate Geometry-Constrained Iminopyridyl Ligands in Cobalt Catalysis: Highly Markovnikov-Selective Hydrosilylation of Alkynes was written by Zong, Zhijian;Yu, Qianwen;Sun, Nan;Hu, Baoxiang;Shen, Zhenlu;Hu, Xinquan;Jin, Liqun. And the article was included in Organic Letters in 2019.Application of 40365-61-5 This article mentions the following:

Reported herein is a well-defined bidentate geometry-constrained iminopyridyl Co complex for an efficient and highly Markovnikov-selective hydrosilylation of alkynes, featuring a broad substrate scope including aromatic/heteroaromatic/aliphatic alkynes and primary/secondary silanes. TON is up to 4950. The kinetic study together with structures clearly revealed that the ligand played the key effect on the efficiency. In the experiment, the researchers used many compounds, for example, 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5Application of 40365-61-5).

2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5) belongs to tetrahydropyran derivatives. Tetrahydropyran is a useful synthetic intermediate. Tetrahydropyranyl (THP-) ethers derived from the reaction of alcohols and dihydropyran are common intermediates in organic synthesis. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.Application of 40365-61-5

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Generation of α,β-unsaturated platinum carbenes from homopropargylic alcohols: rearrangements to polysubstituted furans was written by Allegretti, Paul A.;Ferreira, Eric M.. And the article was included in Organic Letters in 2011.Product Details of 40365-61-5 This article mentions the following:

A number of diversely substituted furans are synthesized via a cycloisomerization process that goes through a unique metal carbene species. Both ligand structure and the nature of the leaving group are evaluated. The characteristics of the carbene intermediate can be modulated, resulting in highly selective hydrogen or silicon group migrations. In the experiment, the researchers used many compounds, for example, 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5Product Details of 40365-61-5).

2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5) belongs to tetrahydropyran derivatives. Tetrahydropyran is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuff. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.Product Details of 40365-61-5

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

A mild and efficient synthesis of chloro esters by cleavage of cyclic and acyclic ethers using Bi(NO₃)₃·5H₂O as catalyst under solvent-free conditions was written by Suresh, V.;Suryakiran, N.;Venkateswarlu, Y.. And the article was included in Canadian Journal of Chemistry in 2007.Application In Synthesis of 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran This article mentions the following:

A facile, efficient synthesis of chloro esters is described. The reaction of cyclic and acyclic ethers with acid chlorides in the presence of catalytic amounts of Bi(NO₃)₃·5H₂O under solvent-free conditions yielded the chloro esters, e.g., THF + AcCl → AcO(CH₂)₄Cl. Also, the catalyst can be recovered conveniently and reused efficiently at least six times. In the experiment, the researchers used many compounds, for example, 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5Application In Synthesis of 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran).

2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5) belongs to tetrahydropyran derivatives. Tetrahydropyran is a useful synthetic intermediate. Tetrahydropyranyl (THP-) ethers derived from the reaction of alcohols and dihydropyran are common intermediates in organic synthesis. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.Application In Synthesis of 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Synthesis of the precursor compound of anti-tumor natural product ainsliatrimer A was written by Chen, Yi;Song, Hao. And the article was included in Huaxi Yaoxue Zazhi in 2012.Recommanded Product: 40365-61-5 This article mentions the following:

The precursor compound of anti-tumor natural product ainsliatrimer A was synthesized. The target precursor compound of anti-tumor natural product ainsliatrimer A was obtained by nucleophilic substitution, Wittig reaction, carbonyl radical addition and other key reactions with starting material of tert-Bu (5-iodopentyloxy) dimethylsilane. The target precursor compound of ainsliatrimer A was successfully synthesized, which laid the foundation for the total synthesis of compounds ainsliatrimer A and ainsliatrimer B, through a 7-step reaction with overall yield of 27.1%. In the experiment, the researchers used many compounds, for example, 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5Recommanded Product: 40365-61-5).

2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5) belongs to tetrahydropyran derivatives. Tetrahydropyran is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuff. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.Recommanded Product: 40365-61-5

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Enantioselective Cobalt-Catalyzed Cascade Hydrosilylation and Hydroboration of Alkynes to Access Enantioenriched 1,1-Silylboryl Alkanes was written by Jin, Shengnan;Liu, Kang;Wang, Shuai;Song, Qiuling. And the article was included in Journal of the American Chemical Society in 2021.Application In Synthesis of 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran This article mentions the following:

Enantioenriched 1,1-silylboryl alkanes possess silyl and boryl groups that are both connected to the same stereogenic carbon center at well-defined orientations. As these chiral multifunctionalized compounds potentially offer two synthetic handles, they are highly valued building blocks in asym. synthesis as well as medicinal chem. Despite the potential usefulness, efficient synthetic approaches for their preparation are scarce. Seeking to address this deficiency, an enantioselective cobalt-catalyzed hydrosilylation/hydroboration cascade of terminal alkynes has been realized. This protocol constitutes an impressive case of chemo-, regio-, and stereoselectivity wherein the two different hydrofunctionalization events are exquisitely controlled by a single set of metal catalyst and ligand, an operation which would usually require two sep. catalytic systems. Downstream transformations of enantioenriched 1,1-silyboryl alkanes led to various valuable chiral compounds Mechanistic studies suggest that the present reaction undergoes highly regioselective and stereocontrolled sequential hydrosilylation and hydroboration processes. In the experiment, the researchers used many compounds, for example, 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5Application In Synthesis of 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran).

2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5) belongs to tetrahydropyran derivatives. Tetrahydropyran is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuff. One classic procedure for the organic synthesis of tetrahydropyran is by hydrogenation of the 3,4-isomer of dihydropyran with Raney nickel.Application In Synthesis of 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Preliminary GC-MS anlaysis and antioxidant study of one ayurvedic medicine “Manasa mitra vatakam” was written by Sivakumaran, G.;Rao, Mudiganti Ram Krishna;Prabhu, K.;Kalaiselvi, V. S.;Jones, Sumathi;Johnson, W. M.;Antony, J.. And the article was included in International Journal of Pharmaceutical Sciences Review and Research in 2016.Recommanded Product: 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran This article mentions the following:

The authenticity of the medicinal efficacy of Ayurvedic and Siddha medicines is of great importance in the present day surge in the use of complimentary and alternative medicines. The present study is a step in this direction. Manasamitra vatakam is an Ayurvedic medicine used for the treatment of mental disorders, anxiety etc. This medicince is made of many components which are of plant, animal and mineral origin. The GC MS anal. revealed the presence of some important biomolecuels like 13-Docosenamide,(Z)-, n- Hexadecanoic acid, Oleic Acid, Borneol, Octadecanoic acid, 9-Octadecenoic acid, (E)-, Isoamyl cinnamate, 1-Heptadecanamine Disilane, 9-Octadecenamide, (Z)-, (diphenylmethyl)pentaphenyl-, Undecanoic acid, 11-amino-, Erucic acid, Tetradecanamide, Squalene among other minor components. These biomols. have reflections on the role of this medicine. The antioxidant study also indicated that this medicine has strong properties as antioxidant. Further study however is warranted to prove the medicinal efficacy of this medicine. In the experiment, the researchers used many compounds, for example, 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5Recommanded Product: 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran).

2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5) belongs to tetrahydropyran derivatives. Numerous natural products have tetrahydropyran skeleton as the building block for designing new natural products and their derivatives e.g. aplysiatoxins, avermectins, oscillatoxins, talaromycins, latrunculins and acutiphycins. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.Recommanded Product: 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

A Photocatalyzed Cascade Approach Toward the Tetracyclic Core of Akuammiline Alkaloids was written by Wang, Qile;Hu, Jie;Zheng, Nan. And the article was included in Organic Letters in 2019.HPLC of Formula: 40365-61-5 This article mentions the following:

A cascade approach toward the tetracyclic core (e.g. I) of akuammiline alkaloids which features high modularity and convergence is reported. Distinct substitution pattern can be readily introduced to the tetracyclic core by varying three building blocks with similar complexity. The critical event in the cascade is a regio- and stereoselective 1,2-shift enabled by a carbocation that sets up the core. In the experiment, the researchers used many compounds, for example, 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5HPLC of Formula: 40365-61-5).

2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran (cas: 40365-61-5) belongs to tetrahydropyran derivatives. Numerous natural products have tetrahydropyran skeleton as the building block for designing new natural products and their derivatives e.g. aplysiatoxins, avermectins, oscillatoxins, talaromycins, latrunculins and acutiphycins. The reaction of tertiary 1,4- and 1,5-diols with cerium ammonium nitrate at room temperature gives tetrahydrofuran and tetrahydropyran derivatives in high yield and stereoselectivity. Various fragrant compounds have been synthesized using this method.HPLC of Formula: 40365-61-5

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics