Xiao, Wenbo et al. published their research in Chemical Communications (Cambridge, United Kingdom) in 2012 | CAS: 13417-49-7

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization. The bismuth chloride-assisted cross-cyclization between homoallylic alcohols and epoxides provided various benzyl tetrahydropyran derivatives. The reaction afforded good yields of desired products and occurred under mild conditions.Synthetic Route of C6H8O2

Ruthenium(IV) porphyrin catalyzed phosphoramidation of aldehydes with phosphoryl azides as a nitrene source was written by Xiao, Wenbo;Zhou, Cong-Ying;Che, Chi-Ming. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2012.Synthetic Route of C6H8O2 This article mentions the following:

[RuIV(por)Cl2] (por = porphyrin dianion) can efficiently catalyze nitrene insertion into aldehyde C-H bonds with phosphoryl azides as a nitrene source to give N-acylphosphoramidates in good to high yields. Thus, treating 4-methylbenzaldehyde with 1.5 equiv of diphenylphosphoryl azide (DPPA) in the presence of 5 mol% [RuIV(TPP)Cl2] (TPP = meso-tetrakis(4-tolyl)porphyrin) in dichloroethane under inert atm. reflux conditions yielded the corresponding di-Ph (4-methylbenzoyl)phosphoramidite (2a) in 92% yield and with 100% substrate conversion. No reaction was observed in the absence of the ruthenium catalyst. The structure of 2a was determined by x-ray crystallog. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Synthetic Route of C6H8O2).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization. The bismuth chloride-assisted cross-cyclization between homoallylic alcohols and epoxides provided various benzyl tetrahydropyran derivatives. The reaction afforded good yields of desired products and occurred under mild conditions.Synthetic Route of C6H8O2

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Misono, Akira et al. published their research in Nippon Kagaku Zasshi in 1966 | CAS: 13417-49-7

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. In organic synthesis, the 2-tetrahydropyranyl group is used as a protecting group for alcohols. Pyran derivatives such as pyran flavonoids are biologically important. Monosaccharides containing six-membered rings are called pyranose.Product Details of 13417-49-7

The hydrodimerization of acrolein by electro-reduction was written by Misono, Akira;Osa, Tetsuo;Yamagishi, Takamichi. And the article was included in Nippon Kagaku Zasshi in 1966.Product Details of 13417-49-7 This article mentions the following:

Electrolytic reduction of CH2:CHCHO (I) was carried out in Et4N+.p-MeC6H4SO3 (II), Bu4N +Br (III), or p-MeC6H4SO3H (IV) solution with Hg cathode. The monomeric products were EtCHO, CH2 :CHCH2OH, and PrOH, the yield being low. In aqueous II, 1-formylcyclopentene (V) and 1-cyclopentenylcarbinol (VI) were formed, whose formation can be explained by considering OHC(CH2)4CHO (VII) formed by β-dimerization of I. In aqueous IV, 3-formyl5,6-dihydro-2H-pyran (VIII) was obtained in addition to V and VI. Some polymers and Hg compound were also obtained. In aqueous II, current efficiency (ηv) for formation of V increased with increasing concentration of II, had a maximum at ∼15 g./120 ml. concentration of I and had a maximum at -1.2 v. cathode potential when the potential was changed. On the other hand, current efficiency (ηpr) for formation of PrOH had a min. at ∼20 g./120 ml. concentration of I. Addition of p-(HO)2C6H4 (IX) did not affect the current efficiency. In aqueous IV, both ηv and ηpr increased with increasing concentration of IV but the effect was strongest for current efficiency for formation of VIII. ηv increased with increasing c.d. and decreased when IX was added. Electrolysis of I in the presence of CH2:CHCO2Et did not give any codimerization product. Polarography of I in aqueous III showed E1/2-1.37 v. which corresponded to reduction of C:C. Addition of IV shifted the half wave potential to -1.30 v. Headhead dimerization is postulated to proceed via addition of monomer anion in nucleophilic fashion to form VII which condenses to on heating. Formation of VIII is attributed to hydration of I followed by addition to form O(CH2CH2CHO)2. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Product Details of 13417-49-7).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. In organic synthesis, the 2-tetrahydropyranyl group is used as a protecting group for alcohols. Pyran derivatives such as pyran flavonoids are biologically important. Monosaccharides containing six-membered rings are called pyranose.Product Details of 13417-49-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Raemy, A. et al. published their research in Calorimetrie et Analyse Thermique in 1982 | CAS: 14431-43-7

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyran is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuff. Pyran derivatives such as pyran flavonoids are biologically important. Monosaccharides containing six-membered rings are called pyranose.Quality Control of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate

Thermal decomposition of carbohydrates studied by heat flow calorimetry was written by Raemy, A.;Schweizer, T.. And the article was included in Calorimetrie et Analyse Thermique in 1982.Quality Control of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate This article mentions the following:

Heat flow calorimetry was used to study the thermal behavior of various mono-, oligo-, and polysaccharides. The samples were analyzed by heating in sealed cells. The temperature range in which exothermic reactions, due to thermal decomposition, occurred, varied widely depending on the type of the carbohydrate. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Quality Control of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyran is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuff. Pyran derivatives such as pyran flavonoids are biologically important. Monosaccharides containing six-membered rings are called pyranose.Quality Control of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Lofroth, Goran et al. published their research in Acta Chemica Scandinavica (1947-1973) in 1967 | CAS: 14431-43-7

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans and furans principally constitute as a central motif in diverse medicinally privileged molecules. There is large number of marine macrolide natural products that contain tetrahydropyran and tetrahydrofuran ring together. For instance, goniodomin A (actin targeting polyether), prorocentrolide (toxin halistatins), and percentotoxineRelated Products of 14431-43-7

Yields in the radiation degradation of solid carbohydrates was written by Lofroth, Goran. And the article was included in Acta Chemica Scandinavica (1947-1973) in 1967.Related Products of 14431-43-7 This article mentions the following:

The degradation induced by γ-irradiation of various simple polycrystalline carbohydrates has been studied by E.S.R. measurements of the solid samples, and by analyses of product formation and reactions occurring when the samples are dissolved in water. The area under the E.S.R. absorption curve is not inversely proportional to the absolute temperature at which the E.S.R. measurements are made, between 160 and 300°K., indicating a possible interaction between the radicals. When the irradiated carbohydrates are dissolved in water, they consume O that is dissolved in the water. It is postulated that radical-oxygen and radical-radical reactions are competitive. The consumption of dissolved O during the reaction was fit to an approx. equation from which the ratio of reaction velocities of radical-oxygen and radical-radical reactions was in the range of 10-15. The glucose(G) value of O consumption at high O concentrations of the water is 4 or higher. The aqueous solutions of the irradiated carbohydrates contain compounds, possibly organic peroxides, that oxidize ferrous ions of the FeSO4 reagent. The G value of ferrous ion oxidation is 4-10 for various carbohydrates. The yield of acids and the total degradation of the carbohydrates are strongly dependent on the crystalline form of the carbohydrate. 53 references. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Related Products of 14431-43-7).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans and furans principally constitute as a central motif in diverse medicinally privileged molecules. There is large number of marine macrolide natural products that contain tetrahydropyran and tetrahydrofuran ring together. For instance, goniodomin A (actin targeting polyether), prorocentrolide (toxin halistatins), and percentotoxineRelated Products of 14431-43-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Chelliah, Mariappan V. et al. published their research in Journal of Medicinal Chemistry in 2007 | CAS: 13417-49-7

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are useful synthons for biologically important compounds. There is large number of marine macrolide natural products that contain tetrahydropyran and tetrahydrofuran ring together. For instance, goniodomin A (actin targeting polyether), prorocentrolide (toxin halistatins), and percentotoxineReference of 13417-49-7

Heterotricyclic Himbacine Analogs as Potent, Orally Active Thrombin Receptor (Protease Activated Receptor-1) Antagonists was written by Chelliah, Mariappan V.;Chackalamannil, Samuel;Xia, Yan;Eagen, Keith;Clasby, Martin C.;Gao, Xiaobang;Greenlee, William;Ahn, Ho-Sam;Agans-Fantuzzi, Jacqueline;Boykow, George;Hsieh, Yunsheng;Bryant, Matthew;Palamanda, Jairam;Chan, Tze-Ming;Hesk, David;Chintala, Madhu. And the article was included in Journal of Medicinal Chemistry in 2007.Reference of 13417-49-7 This article mentions the following:

Pursuing our earlier efforts in the himbacine-based thrombin receptor antagonist area, we have synthesized a series of compounds that incorporate heteroatoms in the C-ring of the tricyclic motif. This effort has resulted in the identification of several potent heterocyclic analogs with excellent affinity for the thrombin receptor. Several of these compounds demonstrated robust inhibition of platelet aggregation in an ex vivo model in cynomolgus monkeys following oral administration. A detailed profile of I, a benchmark compound in this series, with a Ki of 4.3 nM, is presented. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Reference of 13417-49-7).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are useful synthons for biologically important compounds. There is large number of marine macrolide natural products that contain tetrahydropyran and tetrahydrofuran ring together. For instance, goniodomin A (actin targeting polyether), prorocentrolide (toxin halistatins), and percentotoxineReference of 13417-49-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Perez, Serge et al. published their research in Carbohydrate Research in 1998 | CAS: 14431-43-7

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization. There is large number of marine macrolide natural products that contain tetrahydropyran and tetrahydrofuran ring together. For instance, goniodomin A (actin targeting polyether), prorocentrolide (toxin halistatins), and percentotoxineQuality Control of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate

A comparison and chemometric analysis of several molecular mechanics force fields and parameter sets applied to carbohydrates was written by Perez, Serge;Imberty, Anne;Engelsen, Soren B.;Gruza, Jan;Mazeau, Karim;Jimenez-Barbero, Jesus;Poveda, Ana;Espinosa, Juan-Felix;Van Eyck, Bouke P.;Johnson, Glenn;French, Alfred D.;Kouwijzer, Marie Louise C. E.;Grootenuis, Peter D. J.;Bernardi, Anna;Raimondi, Laura;Senderowitz, Hanoch;Durier, Viviane;Vergoten, Gerard;Rasmussen, Kjeld. And the article was included in Carbohydrate Research in 1998.Quality Control of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate This article mentions the following:

Carbohydrates are thought to be especially difficult to model because of their highly polar functionality, their flexibility, and their differences in electronic arrangements that occur during conformational and configurational changes, such as the anomeric, exo-anomeric and gauche effects. These issues have been addressed in recent years, yielding several contributions to set up some relevant parameterizations that would account for these specific features of carbohydrates. Within the framework of a workshop involving the participation of 11 research groups active in the field, several commonly used mol. mechanics force fields and special carbohydrate parameter sets have been considered. The application of 20 force fields and/or sets of parameters to a series of seven test cases provided a fairly general picture of the potentiality of these parameter sets for giving a consistent image of structure and energy of carbohydrate mols. The results derived from a chemometric anal. (principal component anal., PCA) give a global view of the performances of the force fields and parameter sets for carbohydrates. The present anal. (i) provides an identification of the parameter sets which differ from the bulk, (ii) helps to establish the relationship that exists between the different parameter sets, (iii) provides indications for selecting different parameter sets to explore the force field dependency (or the lack of thereof) of a given mol. modeling study. Through the PCA, we have created a force field landscape on which the different force fields are related to each other on a relative scale. New carbohydrate force fields can easily be inserted into this landscape (PCA model) and related to the performance of existing force fields. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Quality Control of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization. There is large number of marine macrolide natural products that contain tetrahydropyran and tetrahydrofuran ring together. For instance, goniodomin A (actin targeting polyether), prorocentrolide (toxin halistatins), and percentotoxineQuality Control of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Horii, Fumitaka et al. published their research in Polymer Bulletin (Berlin, Germany) in 1983 | CAS: 14431-43-7

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.HPLC of Formula: 14431-43-7

Solid-state carbon-13 NMR study of conformations of oligosaccharides and cellulose. Conformation of CH2OH group about the exo-cyclic carbon-carbon bond was written by Horii, Fumitaka;Hirai, Asako;Kitamaru, Ryozo. And the article was included in Polymer Bulletin (Berlin, Germany) in 1983.HPLC of Formula: 14431-43-7 This article mentions the following:

Cross-polarization/dipolar decoupling/magic-angle spinning 13C NMR spectra were obtained for different monosaccharides, oligosaccharides, and cellulose. A simple linear relationship exists between the chem. shift of the CH2OH carbon and the torsion angle χ about the exo-cyclic C-C bond. The chem. shifts fall into three groups of 60-62.6 ppm, 62.5-64.5 ppm, and 65.5-66.5 ppm, which are related to gauche-gauche, gauche-trans, and trans-gauche conformations, resp. On the basis of these results the conformation of the CH2OH carbon of cellulose is also discussed. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7HPLC of Formula: 14431-43-7).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.HPLC of Formula: 14431-43-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Ohshima, Kiyoshi et al. published their research in Japanese Journal of Applied Physics in 1974 | CAS: 14431-43-7

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Dihydropyrans and tetrahydropyrans are examples of cyclic ethers widespread in nature. The bismuth chloride-assisted cross-cyclization between homoallylic alcohols and epoxides provided various benzyl tetrahydropyran derivatives. The reaction afforded good yields of desired products and occurred under mild conditions.SDS of cas: 14431-43-7

Mutual transitions between α-D-glucose and its monohydrate was written by Ohshima, Kiyoshi. And the article was included in Japanese Journal of Applied Physics in 1974.SDS of cas: 14431-43-7 This article mentions the following:

α-D-glucose was converted to the monohydrate by hydration, and inversely α-D-glucose monohydrate was converted back into the anhydrous form by pyrolysis. In these experiments, the crystal surfaces were observed with an optical microscope, and the crystal structures of both glucoses were studied by x-ray diffraction. Glucose monohydrate exists in the form of rod-like and needle-like granules and in the form of a larger grain shaped like a plate. Powder diffraction lines of both glucoses were analyzed. In the discussion of these exptl. results, the mechanism of mutual transitions is made clear. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7SDS of cas: 14431-43-7).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Dihydropyrans and tetrahydropyrans are examples of cyclic ethers widespread in nature. The bismuth chloride-assisted cross-cyclization between homoallylic alcohols and epoxides provided various benzyl tetrahydropyran derivatives. The reaction afforded good yields of desired products and occurred under mild conditions.SDS of cas: 14431-43-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Kiraly, Sandor Balazs et al. published their research in European Journal of Organic Chemistry in 2021 | CAS: 13417-49-7

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Numerous natural products have tetrahydropyran skeleton as the building block for designing new natural products and their derivatives e.g. aplysiatoxins, avermectins, oscillatoxins, talaromycins, latrunculins and acutiphycins. The bismuth chloride-assisted cross-cyclization between homoallylic alcohols and epoxides provided various benzyl tetrahydropyran derivatives. The reaction afforded good yields of desired products and occurred under mild conditions.Recommanded Product: 5,6-Dihydro-2H-pyran-3-carbaldehyde

Knoevenagel-Cyclization Cascade Reactions of Substituted 5,6-Dihydro-2H-Pyran Derivatives was written by Kiraly, Sandor Balazs;Benyei, Attila;Lisztes, Erika;Biro, Tamas;Toth, Balazs Istvan;Kurtan, Tibor. And the article was included in European Journal of Organic Chemistry in 2021.Recommanded Product: 5,6-Dihydro-2H-pyran-3-carbaldehyde This article mentions the following:

The diastereoselective domino-Knoevenagel-IMHDA reactions of 5,6-dihydro-2H-pyran derivatives containing an o-formylaryl amine or ether moiety were performed with active methylene reagents. In the spiro heterocyclic products such as I representing a novel skeleton, a tetrahydroquinoline or chroman unit was fused with two pyran rings and the bridgehead carbon atoms were chirality centers formed diastereoselectively. Depending on the substitution pattern, a domino Knoevenagel-[1,5]-hydride shift-cyclization sequence was identified as a competing pathway, which resulted in the formation of tetrahydroquinoline derivatives such as II with a 5,6-dihydro-2H-pyran-3-yl substituent. The relative configurations of the products were determined by means of the characteristic NOE correlations and single crystal X-ray diffraction anal. Antiproliferative activity assays of two products against A2780 and WM35 human cancer cell lines showed low micromolar IC50 values down to 2.99μM. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Recommanded Product: 5,6-Dihydro-2H-pyran-3-carbaldehyde).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Numerous natural products have tetrahydropyran skeleton as the building block for designing new natural products and their derivatives e.g. aplysiatoxins, avermectins, oscillatoxins, talaromycins, latrunculins and acutiphycins. The bismuth chloride-assisted cross-cyclization between homoallylic alcohols and epoxides provided various benzyl tetrahydropyran derivatives. The reaction afforded good yields of desired products and occurred under mild conditions.Recommanded Product: 5,6-Dihydro-2H-pyran-3-carbaldehyde

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Wu, Haibo et al. published their research in Chemical Science in 2021 | CAS: 13417-49-7

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Dihydropyrans and tetrahydropyrans are examples of cyclic ethers widespread in nature. The bismuth chloride-assisted cross-cyclization between homoallylic alcohols and epoxides provided various benzyl tetrahydropyran derivatives. The reaction afforded good yields of desired products and occurred under mild conditions.Related Products of 13417-49-7

Kinetic resolution of racemic allylic alcohols via iridium-catalyzed asymmetric hydrogenation: scope, synthetic applications and insight into the origin of selectivity was written by Wu, Haibo;Margarita, Cristiana;Jongcharoenkamol, Jira;Nolan, Mark D.;Singh, Thishana;Andersson, Pher G.. And the article was included in Chemical Science in 2021.Related Products of 13417-49-7 This article mentions the following:

Herein, the first iridium catalyzed kinetic resolution of a wide range of trisubstituted secondary and tertiary allylic alcs. R1R4C=CR2CH(OH)R3 [R1 = Me, Ph, 2-thienyl, etc.; R2 = H, Me, Et, etc.; R3 = Et, i-Pr, Ph, etc.; R4 = H, Me] was described. Large selectivity factors were observed in most cases (s up to 211), providing the unreacted starting materials in good yield with high levels of enantiopurity (ee up to >99%). The utility of this method was highlighted in the enantioselective formal synthesis of some bioactive natural products including pumiliotoxin A, inthomycin A and B. DFT studies and a selectivity model concerning the origin of selectivity were also presented. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Related Products of 13417-49-7).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Dihydropyrans and tetrahydropyrans are examples of cyclic ethers widespread in nature. The bismuth chloride-assisted cross-cyclization between homoallylic alcohols and epoxides provided various benzyl tetrahydropyran derivatives. The reaction afforded good yields of desired products and occurred under mild conditions.Related Products of 13417-49-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics