Category: tetrahydropyran

Foster, G. L. published the artcileAcetylenic corrosion inhibitors, Synthetic Route of 27943-46-0, the publication is Industrial and Engineering Chemistry (1959), 825-8, database is CAplus.

The mol. of propargyl alc. is systematically substituted and the corrosion inhibition of the resulting compounds is tested on AISI type 1020 mild steel in 10% HCl at 150°F. and in 15% HCl at 175 and 200°F. for 16 hrs., each solution containing 0.4% of the test substance. Of 39 compounds tested only iodopentynol ICCCMe₂OH is a better inhibitor than propargyl alc. The exptl. results confirm the theory that the triple bond is the focal point of the inhibitory action against acid corrosion.

Industrial and Engineering Chemistry published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, Synthetic Route of 27943-46-0.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Lee, Myung Sun published the artcileInhibition of VHR dual-specificity protein tyrosine phosphatase activity by flavonoids isolated from Scutellaria baicalensis: structure-activity relationships, Recommanded Product: 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, the publication is Planta Medica (2002), 68(12), 1063-1065, database is CAplus and MEDLINE.

Three flavonoids: norwogonin, dihydronorwogonin and baicalein, were isolated from the roots of Scutellaria baicalensis, as potential inhibitors of VHR dual-specificity protein tyrosine phosphatase (DS-PTPase). Norwogonin (IC₅₀ = 1.1μM), dihydronorwogonin (IC₅₀ = 2.9μM) and baicalein (IC₅₀ = 2.4μM) showed potent inhibitory activity toward VHR, but had no inhibitory activity against T-cell protein tyrosine phosphatase or serine/threonine protein phosphatase 1. From comparisons to the inhibitory activities of other similar flavonoids, it could be suggested that the presence of a hydroxy group in the B ring of flavonoids interferes with the inhibitory activity toward VHR DS-PTPase.

Planta Medica published new progress about 69097-99-0. 69097-99-0 belongs to tetrahydropyran, auxiliary class Other Aliphatic Heterocyclic,Benzene,Phenol,Ether,Inhibitor, name is 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, and the molecular formula is C16H14O6, Recommanded Product: 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Ousji, Ons published the artcileComprehensive In Vitro Metabolism Study of Bisphenol A Using Liquid Chromatography-High Resolution Tandem Mass Spectrometry, Related Products of tetrahydropyran, the publication is Chemical Research in Toxicology (2020), 33(6), 1468-1477, database is CAplus and MEDLINE.

Bisphenol A (BPA) metabolism has been investigated using several in vitro models, including human and rat liver microsomes and subcellular (S9) fractions, as well as human-recombinant cytochrome P 450 3A4 (CYP3A4) expressed in Supersomes, for a comprehensive look at all possible metabolic pathways. By an untargeted approach using liquid chromatog. coupled to a high-resolution quadrupole-time-of-flight mass spectrometer, we were able to detect a large number of known Phase I and Phase II metabolites of BPA, as well as several previously uncharacterized ones. A detailed fragmentation study of BPA and its detected metabolites was crucial to confirm structures. Isotope-labeled BPA analogs were highly useful for the structural elucidation of many metabolites. These results contribute to a better understanding of BPA metabolism, including pathways that may introduce addnl. toxicity, as well as help with the assessment of BPA exposure in different biol. matrixes.

Chemical Research in Toxicology published new progress about 267244-08-6. 267244-08-6 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Chiral,Carboxylic acid,Benzene,Phenol,Alcohol,Ether,, name is (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(4-(2-(4-hydroxyphenyl)propan-2-yl)phenoxy)tetrahydro-2H-pyran-2-carboxylic acid, and the molecular formula is C21H24O8, Related Products of tetrahydropyran.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Torii, Sigeru published the artcilePalladium-catalyzed carbonylation to form 2-substituted 1,4-dihydro-4-oxoquinoline, Formula: C10H16O2, the publication is Tetrahedron Letters (1991), 32(2), 237-40, database is CAplus.

Palladium-catalyzed carbonylation of o-H₂NC₆H₄R (R = Br, I) in the presence of R¹CCH (R¹ = alkyl, cyclohexyl, substituted Ph, benzodioxolyl) under proper conditions (20 kg cm^-2 of CO at 120°) gave a variety of substituted dihydrooxoquinolines I in good yields.

Tetrahedron Letters published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C7H13Br, Formula: C10H16O2.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Torii, Sigeru published the artcileA facile hydroxymethylation of acetylene derivatives with paraformaldehyde by use of an electrogenerated base (EG base), SDS of cas: 27943-46-0, the publication is Chemistry Letters (1988), 1977-8, database is CAplus.

Electrolysis of a mixture of paraformaldehyde and terminal acetylene derivatives smoothly provided the corresponding hydroxymethylated compounds in high yields by passing less than 1 F/mol of electricity. Electroreduction of paraformaldehyde generated in situ an efficient base (EG base), which catalyzed hydroxymethylation of the acetylenes.

Chemistry Letters published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C12H20O6, SDS of cas: 27943-46-0.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Torii, Sigeru published the artcileSyntheses of chromones and quinolones via palladium-catalyzed carbonylation of o-iodophenols and anilines in the presence of acetylenes, Synthetic Route of 27943-46-0, the publication is Tetrahedron (1993), 49(31), 6773-84, database is CAplus.

Synthesis of 2-substituted chromones and quinolones has been performed by a Pd-catalyzed carbonylation of o-iodophenols or o-iodoanilines in the presence of terminal acetylenes in a high yield through coupling of halides and acetylenes followed by cyclization as a one-pot reaction.

Tetrahedron published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C12H20O6, Synthetic Route of 27943-46-0.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Hikino, Hiroshi published the artcileSteroids. XXIV. Shidasterone, an insect metamorphosing substance from Blechnum niponicum. Structure, Product Details of C10H16O2, the publication is Chemical & Pharmaceutical Bulletin (1975), 23(7), 1458-79, database is CAplus and MEDLINE.

The structure of shidasterone (I), the phytoecdysone isolated from B. niponicum (Blechnaeceae) was determined Stereoisomers of the cholestane-20,22-diol derivatives were synthesized and their chem. and spectral properties were examined.

Chemical & Pharmaceutical Bulletin published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, Product Details of C10H16O2.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Hu, Li-Xin published the artcileWhat is in Nigerian waters? Target and non-target screening analysis for organic chemicals, SDS of cas: 69097-99-0, the publication is Chemosphere (2021), 131546, database is CAplus and MEDLINE.

Emerging organic contaminants (e.g., active pharmaceutical ingredients and personal care products ingredients) are ubiquitous in the environment and potentially harmful to ecosystems, have gained increasing public attention worldwide. Nevertheless, there is a scarcity of data on these contaminants in Africa. In this study, various types of water samples (wastewater, surface water and tap water) collected from Lagos, Nigeria were analyzed for these chems. by both target and non-target anal. on an UHPLC-Orbitrap-MS/MS. In total, 109 compounds were identified by non-target screening using the online database mzCloud. Level 1 identification confidence was achieved for 13 compounds for which reference standards were available and level 2 was achieved for the rest. In the quant. anal., 18 of 38 target compounds were detected, including the parent compounds and their metabolites. Acetaminophen, sulfamethoxazole, acesulfame, and caffeine were detected in all samples with their highest concentrations at 8000, 5300, 16, and 7700μg/L in wastewater, 140000, 3300, 7.7, and 12000μg/L in surface water, and 66, 62, 0.17 and 1000μg/L in tap water, resp. The occurrence of psychoactive substances, anticancer treatments, antiretrovirals, antihypertensives, antidiabetics and their metabolites were reported in Nigeria for the first time. These results indicate poor wastewater treatment and management in Nigeria, and provide a preliminary profile of organic contaminants occurring in Nigerian waters. The findings from this study urge more future research on chem. pollution in the aquatic environments in Nigeria.

Chemosphere published new progress about 69097-99-0. 69097-99-0 belongs to tetrahydropyran, auxiliary class Other Aliphatic Heterocyclic,Benzene,Phenol,Ether,Inhibitor, name is 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, and the molecular formula is C16H14O6, SDS of cas: 69097-99-0.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Wang, Ren-Qi published the artcileCationic cyclodextrins chemically-bonded chiral stationary phases for high-performance liquid chromatography, Safety of 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, the publication is Analytica Chimica Acta (2012), 121-129, database is CAplus and MEDLINE.

Two covalently bonded cationic β-CD chiral stationary phases (CSPs) prepared by graft polymerization of 6^A-(3-vinylimidazolium)-6-deoxyperphenylcarbamate-β-cyclodextrin chloride or 6^A-(N,N-allylmethylammonium)-6-deoxyperphenylcarbamoyl-β-cyclodextrin chloride onto silica gel were successfully applied in HPLC. Their enantioseparation capability was examined with 12 racemic pharmaceuticals and 6 carboxylic acids. Imidazolium-containing β-CD CSP afforded more favorable enantioseparations than that containing ammonium moiety under normal-phase HPLC. The cationic moiety on β-CD CSPs could form strong hydrogen bonding with analytes in normal-phase liquid chromatog. (NPLC) to enhance the analytes’ retention and enantioseparations In reversed-phase liquid chromatog. (RPLC), the analytes exhibited their maximum retention when the pH of mobile phase was close to their pK _a value. Inclusion complexation with CD cavity and columbic/ionic interactions with cationic substituent on the CD rim would afford accentuated retention and enantioseparations of the analytes.

Analytica Chimica Acta published new progress about 69097-99-0. 69097-99-0 belongs to tetrahydropyran, auxiliary class Other Aliphatic Heterocyclic,Benzene,Phenol,Ether,Inhibitor, name is 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, and the molecular formula is C8H10O2, Safety of 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Wang, Ren-Qi published the artcileChemically bonded cationic β-cyclodextrin derivatives and their applications in supercritical fluid chromatography, Application In Synthesis of 69097-99-0, the publication is Journal of Chromatography A (2012), 97-103, database is CAplus and MEDLINE.

Cationic β-cyclodextrin (CD) perphenylcarbamoylated derivatives were chem. bonded onto vinylized silica using a radical co-polymerization reaction. The derived materials were used as chiral stationary phases (CSP) in supercritical fluid chromatog. (SFC). Enantioseparations were successfully demonstrated on 14 racemates encompassing flavanones, thiazides and amino acid derivatives The electrostatic force between the analytes and the cationic moiety on β-CD derivative is important for retention and enantioseparation of the racemates. Aromatic cationic moiety on β-CD enabled better enantioseparations than aliphatic cationic moiety. Also the presence of acid additives would result in lower retention of the analytes but often assist the chiral resolutions

Journal of Chromatography A published new progress about 69097-99-0. 69097-99-0 belongs to tetrahydropyran, auxiliary class Other Aliphatic Heterocyclic,Benzene,Phenol,Ether,Inhibitor, name is 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, and the molecular formula is C10H2F12NiO4, Application In Synthesis of 69097-99-0.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics